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The raw material for the recalled heparin batches was processed in China from pig's intestines by the American pharmaceutical firm Scientific Protein Laboratories. [1] [2] [3] The U.S. Food and Drug Administration was quoted as stating that at least 81 deaths were believed to be linked to a raw heparin ingredient imported from the People's Republic of China, and that they had also received 785 ...
Heparin production experienced a break in the 1990s. Until then, heparin was mainly obtained from cattle tissue, which was a by-product of the meat industry, especially in North America. With the rapid spread of BSE, more and more manufacturers abandoned this source of supply. As a result, global heparin production became increasingly ...
In the 1980s low molecular-weight heparin (LMWH) were developed. They are derived from heparin by enzymatic or chemical depolymerization and have better pharmacokinetic properties than heparin. In 1955 the first clinical use of warfarin, a vitamin K antagonist, was reported. Warfarin was originally used as a rat poison in 1948 and thought to be ...
Specialty. Hematology. Heparin-induced thrombocytopenia (HIT) is the development of thrombocytopenia (a low platelet count), due to the administration of various forms of heparin, an anticoagulant. HIT predisposes to thrombosis (the abnormal formation of blood clots inside a blood vessel). When thrombosis is identified the condition is called ...
Timeline of Chinese history. This is a timeline of Chinese history, comprising important legal and territorial changes and political events in China and its dynasties. To read about the background to these events, see History of China. See also the list of Chinese monarchs, Chinese emperors family tree, dynasties of China and years in China.
May. A 7.9-magnitude earthquake in Sichuan, China killed nearly 88,000 people. May 11 – China Commercial Aircraft Corporation (COMAC) was founded. [citation needed] May 12 – 2008 Sichuan earthquake: Over 70,000 killed in central south-west China by the Wenchuan quake, an earthquake measuring 7.9 Moment magnitude scale.
The economic history of China describes the changes and developments in China's economy from the founding of the People's Republic of China (PRC) in 1949 to the present day. The speed of China's transformation in this period from one of the poorest countries to one of the world's largest economies is unmatched in history. [1]: 11.
Formula. C288H448N80O110S6. Molar mass. 6 983.56 g·mol −1. N Y (what is this?) (verify) Lepirudin is an anticoagulant that functions as a direct thrombin inhibitor. Brand name: Refludan, Generic: Lepirudin rDNA for injection. Lepirudin is a recombinant hirudin [1] derived from yeast cells. Lepirudin is almost identical to hirudin extracted ...