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  2. 2008 Chinese heparin adulteration - Wikipedia

    en.wikipedia.org/wiki/2008_Chinese_heparin...

    The raw material for the recalled heparin batches was processed in China from pig's intestines by the American pharmaceutical firm Scientific Protein Laboratories. [1] [2] [3] The U.S. Food and Drug Administration was quoted as stating that at least 81 deaths were believed to be linked to a raw heparin ingredient imported from the People's Republic of China, and that they had also received 785 ...

  3. Heparin - Wikipedia

    en.wikipedia.org/wiki/Heparin

    Heparin production experienced a break in the 1990s. Until then, heparin was mainly obtained from cattle tissue, which was a by-product of the meat industry, especially in North America. With the rapid spread of BSE, more and more manufacturers abandoned this source of supply. As a result, global heparin production became increasingly ...

  4. Low-molecular-weight heparin - Wikipedia

    en.wikipedia.org/wiki/Low-molecular-weight_heparin

    4-6 kDa. Low-molecular-weight heparin (LMWH) is a class of anticoagulant medications. [1] They are used in the prevention of blood clots and, in the treatment of venous thromboembolism (deep vein thrombosis and pulmonary embolism), and the treatment of myocardial infarction. Heparin is a naturally occurring polysaccharide that inhibits ...

  5. Deep vein thrombosis - Wikipedia

    en.wikipedia.org/wiki/Deep_vein_thrombosis

    From 0.8–2.7 per 1000 people per year, but populations in China and Korea are below this range [8] Deep vein thrombosis ( DVT ) is a type of venous thrombosis involving the formation of a blood clot in a deep vein , most commonly in the legs or pelvis.

  6. Anticoagulant - Wikipedia

    en.wikipedia.org/wiki/Anticoagulant

    However, it did increase the risk of major bleeding in 107 more people per 1000 population and minor bleeding in 167 more people per 1000 population. [44] Apixaban had no effect on mortality, recurrence of blood clots in blood vessels, or major or minor bleeding. However, this finding comes only from one study. [44]

  7. Demographics of Florida - Wikipedia

    en.wikipedia.org/wiki/Demographics_of_Florida

    Between the 2010 and 2020 census, the population of the state overall did increase. 50 counties in Florida would experience population growth while 17 counties saw their populations decline. Most of Florida's population lives in urban areas as in the 2020 census, close to 97% of people in Florida resided in metropolitan areas. [ 9 ]

  8. Discovery and development of direct thrombin inhibitors

    en.wikipedia.org/wiki/Discovery_and_development...

    In the 1980s low molecular-weight heparin (LMWH) were developed. They are derived from heparin by enzymatic or chemical depolymerization and have better pharmacokinetic properties than heparin. In 1955 the first clinical use of warfarin, a vitamin K antagonist, was reported. Warfarin was originally used as a rat poison in 1948 and thought to be ...

  9. Protamine sulfate - Wikipedia

    en.wikipedia.org/wiki/Protamine_sulfate

    100.113.361. Protamine sulfate is a medication that is used to reverse the effects of heparin. [3] It is specifically used in heparin overdose, in low molecular weight heparin overdose, and to reverse the effects of heparin during delivery and heart surgery. [3][4] It is given by injection into a vein. [3]