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In the absence of antibiotics or other stressors, filamentation occurs at a low frequency in bacterial populations (4–8% short filaments and 0–5% long filaments in 1- to 8-hour cultures). [3] The increased cell length can protect bacteria from protozoan predation and neutrophil phagocytosis by making ingestion of cells more difficult.
This is most likely due to a mechanism allowing the cell to sense changes within the environment, thus influencing change in gene expression. [62] Understanding how these strain changes occur from being low or non-pathogenic to being highly pathogenic and vice versa may aid in developing novel therapeutics for microbial infections.
The structure of the Bacterial Microcompartment shell. The first structure of a BMC shell, determined by X-ray crystallography and cryo-electron microscopy, [1] contains representatives of each of the shell protein types: BMC-P, BMC-H and BMC-T, in both its trimer (upper right) and dimer of trimer (lower right), forms.
On one hand, a phenotypic switch of the colonizer Curvibacter takes place. The most likely explanation is that the binding of 3-oxo-HSL and 3-hydroxy-HSL causes different conformational changes in the AHL receptors curR1 and curR2. As a result, there is a different DNA-binding motif affinity and thereby different target genes are activated. [17]
The Journal of Bacteriology is a monthly peer-reviewed scientific journal established in 1916. It is published by the American Society for Microbiology and the editor in chief is George A. O'Toole Jr. ( Dartmouth College ).
One example of a bacterial virulence factor acting like a eukaryotic protein is Salmonella protein SopE it acts as a GEF, turning the GTPase on to create more GTP. It does not modify anything, but overdrives normal cellular internalization process, making it easier for the Bacteria to be colonized within a host cell.
Bacterial proteins that need to be secreted pass from the bacterial cytoplasm through the needle directly into the host cytoplasm. Three membranes separate the two cytoplasms: the double membranes (inner and outer membranes) of the Gram-negative bacterium and the eukaryotic membrane. The needle provides a smooth passage through those highly ...
TSST-1 is a bacterial exotoxin found in patients who have developed toxic shock syndrome (TSS), which can be found in menstruating women or any man or child for that matter. [3] One-third of all TSS cases have been found in men. [4] This statistic could possibly be due to surgical wounds or any skin wound. [4]