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  2. Antiandrogen - Wikipedia

    en.wikipedia.org/wiki/Antiandrogen

    Legal status. In Wikidata. Antiandrogens, also known as androgen antagonists or testosterone blockers, are a class of drugs that prevent androgens like testosterone and dihydrotestosterone (DHT) from mediating their biological effects in the body. They act by blocking the androgen receptor (AR) and/or inhibiting or suppressing androgen ...

  3. Androgen deprivation therapy - Wikipedia

    en.wikipedia.org/wiki/Androgen_deprivation_therapy

    Androgen deprivation therapy. Androgen deprivation therapy (ADT), also called androgen ablation therapy or androgen suppression therapy, is an antihormone therapy whose main use is in treating prostate cancer. Prostate cancer cells usually require androgen hormones, such as testosterone, to grow. ADT reduces the levels of androgen hormones ...

  4. Gonadotropin-releasing hormone antagonist - Wikipedia

    en.wikipedia.org/wiki/Gonadotropin-releasing...

    The reduction in testosterone levels that occurs during GnRH antagonist therapy subsequently reduces the size of the prostate cancer. This in turn results in a reduction in prostate-specific antigen (PSA) levels in the patient's blood and so measuring PSA levels is a way to monitor how patients with prostate cancer are responding to treatment ...

  5. Degarelix - Wikipedia

    en.wikipedia.org/wiki/Degarelix

    Degarelix. Degarelix, sold under the brand name Firmagon among others, is a hormonal therapy used in the treatment of prostate cancer. [3][5] Testosterone is a male hormone that promotes growth of many prostate tumours and therefore reducing circulating testosterone to very low (castration) levels is often the treatment goal in the management ...

  6. 5α-Reductase inhibitor - Wikipedia

    en.wikipedia.org/wiki/5α-reductase_inhibitor

    In Wikidata. 5α-Reductase inhibitors (5-ARIs), also known as dihydrotestosterone (DHT) blockers, are a class of medications with antiandrogenic effects which are used primarily in the treatment of enlarged prostate and scalp hair loss. They are also sometimes used to treat excess hair growth in women and as a component of hormone therapy for ...

  7. Bicalutamide - Wikipedia

    en.wikipedia.org/wiki/Bicalutamide

    Bicalutamide, sold under the brand name Casodex among others, is an antiandrogen medication that is primarily used to treat prostate cancer. [10] It is typically used together with a gonadotropin-releasing hormone (GnRH) analogue or surgical removal of the testicles to treat metastatic prostate cancer (mPC).

  8. Discovery and development of antiandrogens - Wikipedia

    en.wikipedia.org/wiki/Discovery_and_development...

    Discovery and development of antiandrogens. The first antiandrogen was discovered in the 1960s. Antiandrogens antagonise the androgen receptor (AR) and thereby block the biological effects of testosterone and dihydrotestosterone (DHT). Antiandrogens are important for men with hormonally responsive diseases like prostate cancer, benign prostatic ...

  9. Can Finasteride Lower Testosterone? (& Other Potential Side ...

    www.aol.com/finasteride-lower-testosterone-other...

    Research shows that taking 5 milligrams (mg) of finasteride a day for benign prostatic hyperplasia (BPH) — an enlarged prostate — can lead to a 15 to 25 percent increase in testosterone levels.

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