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  2. Acral lentiginous melanoma - Wikipedia

    en.wikipedia.org/wiki/Acral_lentiginous_melanoma

    Acral lentiginous melanoma. Acral lentiginous melanoma is a type of skin cancer. [6] It typically begins as a uniform brownish mark before becoming darker and wider with a blurred irregular edge, most frequently seen in the foot of a person with darker skin. [6] It may become bumpy and ulcerate. [6]

  3. Melanoma - Wikipedia

    en.wikipedia.org/wiki/Melanoma

    Melanoma is the most dangerous type of skin cancer; it develops from the melanin -producing cells known as melanocytes. [ 1 ] It typically occurs in the skin, but may rarely occur in the mouth, intestines, or eye (uveal melanoma). [ 1 ][ 2 ] In women, melanomas most commonly occur on the legs; while in men, on the back. [ 2 ]

  4. Melanonychia - Wikipedia

    en.wikipedia.org/wiki/Melanonychia

    Melanonychia is a black or brown pigmentation of a nail, and may be present as a normal finding on many digits in Afro-Caribbeans, as a result of trauma, systemic disease, or medications, or as a postinflammatory event from such localized events as lichen planus or fixed drug eruption.

  5. Melanocyte - Wikipedia

    en.wikipedia.org/wiki/Melanocyte

    Melanocytes are melanin -producing neural crest -derived [3] cells located in the bottom layer (the stratum basale) of the skin's epidermis, the middle layer of the eye (the uvea), [4] the inner ear, [5] vaginal epithelium, [6] meninges, [7] bones, [8] and heart found in many mammals and birds. [9] Melanin is a dark pigment primarily ...

  6. Types of Rheumatic Diseases and How They Affect You - AOL

    www.aol.com/types-rheumatic-diseases-affect...

    It can also cause very swollen fingers and toes (a symptom called dactylitis), problems with nails, such as pitting or nailbed separation, tendon inflammation (enthesopathy), and low back pain ...

  7. Nail disease - Wikipedia

    en.wikipedia.org/wiki/Nail_disease

    A nail disease or onychosis is a disease or deformity of the nail. Although the nail is a structure produced by the skin and is a skin appendage, nail diseases have a distinct classification as they have their own signs and symptoms which may relate to other medical conditions. Some nail conditions that show signs of infection or inflammation ...

  8. Hyperpigmentation - Wikipedia

    en.wikipedia.org/wiki/Hyperpigmentation

    Hyperpigmentation can be diffuse or focal, affecting such areas as the face and the back of the hands. Melanin is produced by melanocytes at the lower layer of the epidermis. Melanin is a class of pigment responsible for producing color in the body in places such as the eyes, skin, and hair. The process of melanin synthesis (melanogenesis ...

  9. Whitlow - Wikipedia

    en.wikipedia.org/wiki/Whitlow

    Whitlow usually refers to herpetic whitlow, though it can also refer to melanotic whitlow (subungual melanoma), [7] which somewhat resembles acral lentiginous melanoma. The terms whitlow and felon are also sometimes misapplied to paronychia, which is an infection of the tissue at the side or base of the nail. Felon presents with a throbbing ...