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  2. Cialis Side Effects: What to Expect (& How to Avoid Them) - AOL

    www.aol.com/cialis-side-effects-expect-avoid...

    Cialis has an impressively long half-life — one dose can last up to 36 hours (hence, its nickname “the weekend pill”). But you can also take Cialis daily at a lower dose if you’re the ...

  3. Tadalafil: Your Ultimate Guide to Dosages, Side Effects & More

    www.aol.com/tadalafil-ultimate-guide-dosages...

    In elderly men, for instance, tadalafil has a slightly longer half-life of roughly 21.6 hours. As a long-lasting ED medication, tadalafil is only recommended for use one time per day.

  4. Is It Safe to Take Cialis Daily? - AOL

    www.aol.com/safe-cialis-daily-115900442.html

    Daily Cialis Dosage. Cialis for daily use comes in two dosages: 2.5mg and 5mg. That’s about a quarter of what’s prescribed for as-needed use, where Cialis typically comes in two different ...

  5. Tadalafil - Wikipedia

    en.wikipedia.org/wiki/Tadalafil

    Tadalafil, sold under the brand name Cialis among others, is a medication used to treat erectile dysfunction, benign prostatic hyperplasia, and pulmonary arterial hypertension. [5] [6] [8] It is taken by mouth. [8] Onset is typically within half an hour and the duration is up to 36 hours. [8]

  6. Biological half-life - Wikipedia

    en.wikipedia.org/wiki/Biological_half-life

    So, for example, digoxin has a half-life (or t ⁠ 1 / 2 ⁠) of 24–36 h; this means that a change in the dose will take the best part of a week to take full effect. For this reason, drugs with a long half-life (e.g., amiodarone , elimination t ⁠ 1 / 2 ⁠ of about 58 days) are usually started with a loading dose to achieve their desired ...

  7. Effective half-life - Wikipedia

    en.wikipedia.org/wiki/Effective_half-life

    Alternatively, since the radioactive decay contributes to the "physical (i.e. radioactive)" half-life, while the metabolic elimination processes determines the "biological" half-life of the radionuclide, the two act as parallel paths for elimination of the radioactivity, the effective half-life could also be represented by the formula: [1] [2]

  8. Cialis vs. Viagra: How Are They Different? - AOL

    www.aol.com/cialis-vs-viagra-different-175700354...

    As we mentioned, most of the time, side effects from ED medications get better over time. But because Cialis has a much longer half-life than Viagra, you may experience Cialis side effects for longer.

  9. Icos - Wikipedia

    en.wikipedia.org/wiki/Icos

    Cialis was approved in Europe in November 2002 and in the United States a year later. [10] The drug was approved for once-daily use for ED in Europe in June 2007 and in the United States in January 2008. [15] [16] In 2006, Cialis generated $971 million in sales, [16] leading Icos to post its first-ever quarterly profit in August. [3]

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