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  2. Strain (chemistry) - Wikipedia

    en.wikipedia.org/wiki/Strain_(chemistry)

    The steric strain between the two terminal methyl groups accounts for the difference in energy between the two similar, yet very different conformations ...

  3. Rotamer - Wikipedia

    en.wikipedia.org/wiki/Rotamer

    a torsion angle between 90° and 150° or −90° and −150° is called anticlinal (ac) a torsion angle between ±150° and 180° is called antiperiplanar (ap), also called anti-or trans-conformation; Torsional strain or "Pitzer strain" refers to resistance to twisting about a bond.

  4. Cyclohexane conformation - Wikipedia

    en.wikipedia.org/wiki/Cyclohexane_conformation

    The interaction between the two flagpole hydrogens, in particular, generates steric strain. Torsional strain also exists between the C2–C3 and C5–C6 bonds (carbon number 1 is one of the two on a mirror plane), which are eclipsed — that is, these two bonds are parallel one to the other across a mirror plane. Because of this strain, the ...

  5. Steric effects - Wikipedia

    en.wikipedia.org/wiki/Steric_effects

    Steric hindrance is often exploited to control selectivity, such as slowing unwanted side-reactions. Steric hindrance between adjacent groups can also affect torsional bond angles. Steric hindrance is responsible for the observed shape of rotaxanes and the low rates of racemization of 2,2'-disubstituted biphenyl and binaphthyl derivatives.

  6. Van der Waals strain - Wikipedia

    en.wikipedia.org/wiki/Van_der_Waals_strain

    Van der Waals strain is strain resulting from Van der Waals repulsion when two substituents in a molecule approach each other with a distance less than the sum of their Van der Waals radii. Van der Waals strain is also called Van der Waals repulsion and is related to steric hindrance . [ 1 ]

  7. Eclipsed conformation - Wikipedia

    en.wikipedia.org/wiki/Eclipsed_conformation

    In chemistry an eclipsed conformation is a conformation in which two substituents X and Y on adjacent atoms A, B are in closest proximity, implying that the torsion angle X–A–B–Y is 0°. [1] Such a conformation can exist in any open chain, single chemical bond connecting two sp 3 - hybridised atoms, and it is normally a conformational ...

  8. A value - Wikipedia

    en.wikipedia.org/wiki/A_value

    These types of steric interactions are commonly known as 1,3 diaxial interactions. [2] These types of interactions are not present with substituents at the equatorial position. There are generally considered three principle contributions to the conformational free energy: [3] Baeyer strain, defined as the strain arising from deformation of bond ...

  9. Ring strain - Wikipedia

    en.wikipedia.org/wiki/Ring_strain

    Ring strain theory was first developed by German chemist Adolf von Bayer in 1890. Previously, the only bonds believed to exist were torsional and steric; however, Bayer's theory became based on the interactions between the two strains. Bayer's theory was based on the assumption that ringed compounds were flat.