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Betahistine, sold under the brand name Serc among others, is an anti-vertigo medication. It is commonly prescribed for balance disorders or to alleviate vertigo symptoms . It was first registered in Europe in 1970 for the treatment of Ménière's disease, but current evidence does not support its efficacy in treating it.
An H 3 receptor antagonist is a type of antihistaminic drug used to block the action of histamine at H 3 receptors.. Unlike the H 1 and H 2 receptors which have primarily peripheral actions, but cause sedation if they are blocked in the brain, H 3 receptors are primarily found in the brain and are inhibitory autoreceptors located on histaminergic nerve terminals, which modulate the release of ...
Potentiates CNS sedatives, [3] chronic use might cause a reversible dry skin condition. [18] Khat: qat Catha edulis: Chronic liver dysfunction [3] [19] Kratom: Mitragyna speciosa: Hepatotoxicity [20] [19] Liquorice root Glycyrrhiza glabra: Hypokalemia, hypertension, arrhythmias, edema [5] Lobelia: asthma weed, pukeweed, vomit wort Lobelia inflata
A histamine agonist is a drug which causes increased activity at one or more of the four histamine receptor subtypes. H 1 agonists promote wakefulness. [1] H 2: Betazole and Impromidine are examples of agonists used in diagnostics to increase histamine. H 3: Betahistine is a weak Histamine 1 agonist and a very strong antagonist of the Histamine ...
Often, a specific cause is not identified. [3] When found, the underlying mechanism typically involves a small calcified otolith moving around loose in the inner ear. [3] Diagnosis is typically made when the Dix–Hallpike test results in nystagmus (a specific movement pattern of the eyes) and other possible causes have been ruled out. [1]
As of 2014, betahistine is often used as it is inexpensive and safe; [5] but evidence does not justify its use in Ménière's disease. [ 36 ] [ 37 ] However, recent pharmacokinetic experiments have shown that combination therapy with Monoamine oxidase inhibitors can drastically increase the bioavailability of betahistine in humans, [ 38 ] and ...
The evidence does not report how antihistamines affect women differently than men. [1] Different studies have reported on antihistamine use in children, with various studies finding evidence that certain antihistamines could be used by children 2 years of age, and other drugs being safer for younger or older children. [1]
Common side effects include sleepiness, dry mouth, constipation, and trouble with vision. [5] More serious side effects include low blood pressure and urinary retention. [5] It is not generally recommended in young children or those with glaucoma. [2] [6] Cyclizine appears to be safe during pregnancy but has not been well studied. [7]
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