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Intake of large doses (2.0 to 4.0 g/day) of long-chain omega−3 fatty acids as prescription drugs or dietary supplements are generally required to achieve significant (> 15%) lowering of triglycerides, and at those doses the effects can be significant (from 20% to 35% and even up to 45% in individuals with levels greater than 500 mg/dL).
Oils from seeds have the lowest percentage of saturated fat, and range widely in their composition of omega-3, omega-6, and omega-9. Main article: Omega-6 fatty acid § Health effects Sunflower , corn , and soybean oil have a higher proportion of omega-6 fatty acids than oils from fish , walnuts , flaxseed , and rapeseed (canola).
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A 2019 review found that omega−3 fatty acid supplements make little or no difference to cardiovascular mortality and that people with myocardial infarction have no benefit in taking the supplements. [125] A 2021 review found that omega−3 supplementation did not affect cardiovascular disease outcomes. [10]
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