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Bronchoscopic lung volume reduction (BLVR) is a procedure to reduce the volume of air within the lungs. BLVR was initially developed in the early 2000s [ 1 ] [ 2 ] as a minimally invasive treatment for severe COPD that is primarily caused by emphysema .
The concentration of carbon dioxide (CO 2) rises in the blood when the metabolic use of oxygen (O 2), and the production of CO 2 is increased during, for example, exercise. The CO 2 in the blood is transported largely as bicarbonate (HCO 3 − ) ions, by conversion first to carbonic acid (H 2 CO 3 ), by the enzyme carbonic anhydrase , and then ...
Dual-control modes of ventilation are auto-regulated pressure-controlled modes of mechanical ventilation with a user-selected tidal volume target. The ventilator adjusts the pressure limit of the next breath as necessary according to the previous breath's measured exhaled tidal volume.
Modes of mechanical ventilation are one of the most important aspects of the usage of mechanical ventilation.The mode refers to the method of inspiratory support. In general, mode selection is based on clinician familiarity and institutional preferences, since there is a paucity of evidence indicating that the mode affects clinical outcome.
Emphysema. Collateral ventilation is a back-up system of alveolar ventilation that can bypass the normal route of airflow when airways are restricted or obstructed. The pathways involved include those between adjacent alveoli (pores of Kohn), between bronchioles and alveoli (canals of Lambert), and those between bronchioles (channels of Martin).
Lung volume reduction may be offered to those with advanced emphysema. When other treatments fail, and the emphysema is in the upper lobes, a surgical option may be possible. [ 49 ] A number of minimally invasive bronchoscopic procedures are increasingly used to reduce lung volume.
Inspiratory pump inserts a volume of PFC in the lungs (valve 1 open, valve 2 closed), and the expiratory pump pushes PFC in the oxygenator via the filter (valve 3 closed, valve 4 open). During the inspiratory pause (all valves are closed), the lung volume is at its maximal value. The measured pressure is the Positive End-Inspiratory Pressure ...
Restrictive lung diseases are a category of extrapulmonary, pleural, or parenchymal respiratory diseases that restrict lung expansion, [2] resulting in a decreased lung volume, an increased work of breathing, and inadequate ventilation and/or oxygenation. Pulmonary function test demonstrates a decrease in the forced vital capacity.