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Polyhexamethylene guanidine (PHMG) is a guanidine derivative that is used as a biocidal disinfectant, often in the form of its salt polyhexamethylene guanidine phosphate (PHMG-P). Studies have shown that PHMG in solution has fungicidal as well as bactericidal activity against both Gram-positive and Gram-negative bacteria . [ 2 ]
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In 1998, PHMG was founded as PleaseHoldUK in Chester, England.Its office relocated to Manchester in 2000, where the global headquarters has been based since. The agency has rebranded several times. PleaseHoldUK became PH Media Group in 2008, before transitioning to PHMG in 2016. Following significant growth into new territories, the company underwent its most recent
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Experiments by the South Korean government found pulmonary toxicity of PHMG and PGH when inhaled as a vapor. [4] [5] PHMG and PGH caused pulmonary fibrosis when experimented on animals. On November 11, 2011, six humidifier disinfectants which contain PHMG and PGH were recovered. PHMG and PGH was banned in 2011, and new cases ceased occurring.
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