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Congenital Hypertrophy of the Retinal Pigment Epithelium = CHRPE lesions ... and lacunae or loss of RPE ...
CHRPE fundus flat, dark gray-black lesion. Enlarge Download. Image Permissions: Ophthalmic Atlas Images by ...
Figure 2. Right eye in 2006. In 2006, best corrected visual acuity was 20/15 OD and count fingers OS. There was a left exotropia and central scotoma OS.
DISCUSSION. Etiology/Epidemiology. First described as a solitary hypopigmented nevus by Roseman and Gass in 1992, torpedo maculopathy (TM) is a rare, benign congenital abnormality of the retinal pigment epithelium (RPE), leading to changes in the architecture of the outer retinal layers.[1]
Small area of congenital hypertrophy of the retinal pigment epithelium (CHRPE) in the left eye, as noted. No previous eye surgery, inflammation, or any history of eye trauma. Medical History: Unremarkable. Complete review of systems did not reveal any history of inflammatory disease, prior infection, infantile illness or sexually transmitted ...
Congenital hypertrophy of the retinal pigmented epithelium (CHRPE) lesions are typically solitary, flat, well-demarcated, hyperpigmented lesions of the retina. They can occasionally be seen in a grouped configuration resembling the footprint of an animal, or "bear tracks," as is seen in this photo. Both solitary lesions and "bear tracks" are ...
Aicardi syndrome is an X-linked dominant condition that is characterized by the triad of round, depigmented chorioretinal lacunae, agenesis of the corpus collosum, and infantile spasms. It can also be associated with optic nerve colobomas and microphthalmos. The condition is almost always seen in females as it is usually lethal in males.
OCULAR EXAMINATION . Visual Acuity without correction. Distance: Right eye (OD) 20/20, Left Eye (OS) 20/40 ; Near: OD 20/20, OS 20/80
Melanocytomas are black, often extend onto the optic nerve and invade the nerve fiber layer, giving a feathered appearance. Congenital hyperplasia of the RPE (CHRPE) is typically a sharply demarcated pigmented lesion with scalloped margins (3). There are several clinical elements that suggest choroidal melanoma on exam:
Reference: Rothova A. Ocular manifestations of toxoplasmosis (Review). Curr Opin Ophthalmol 2003;14(6):384-388.