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The mechanisms behind allergic asthma—i.e., asthma resulting from an immune response to inhaled allergens—are the best understood of the causal factors. In both people with asthma and people who are free of the disease, inhaled allergens that find their way to the inner airways are ingested by a type of cell known as antigen-presenting ...
Asthma phenotyping and endotyping is a novel approach to asthma classification inspired by precision medicine.It seeks to separate the clinical presentations or clusters of signs and symptoms of asthma, known as asthma phenotypes, from their underlying etiologies or causes, known as asthma endotypes.
Asthma phenotyping and endotyping has emerged as a novel approach to asthma classification inspired by precision medicine which separates the clinical presentations of asthma, or asthma phenotypes, from their underlying causes, or asthma endotypes. The best-supported endotypic distinction is the type 2-high/type 2-low distinction.
It is classically reduced in obstructive lung disorders such as asthma. Due to the wide range of 'normal' values and the high degree of variability, peak flow is not the recommended test to identify asthma. However, it can be useful in some circumstances. A small portion of people with asthma may benefit from regular peak flow monitoring. When ...
Asthma triggers are factors or stimuli that provoke the exacerbation of asthma symptoms or increase the degree of airflow disruption, which can lead to an asthma attack. [1] An asthma attack is characterized by an obstruction of the airway , hypersecretion of mucus and bronchoconstriction due to the contraction of smooth muscles around the ...
Treatment Improving cardiac function , maintaining blood oxygen saturation levels, stabilizing total body water volume and distribution Cardiac asthma is the medical condition of intermittent wheezing , coughing, and shortness of breath that is associated with underlying congestive heart failure (CHF). [ 1 ]
Brittle asthma is a type of asthma distinguishable from other forms by recurrent, severe attacks. [ 1 ] [ 2 ] [ 3 ] There are two subtypes divided by symptoms: Type 1 and Type 2, [ 4 ] depending on the stability of the patient's maximum speed of expiration, or peak expiratory flow rate (PEFR).
Acute severe asthma, also known as status asthmaticus, is an acute exacerbation of asthma that does not respond to standard treatments of bronchodilators (inhalers) and corticosteroids. [2] Asthma is caused by multiple genes , some having protective effect, with each gene having its own tendency to be influenced by the environment although a ...