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Naltrexone/bupropion is indicated, as an adjunct to a reduced-calorie diet and increased physical activity, as anti-obesity medication for the management of weight in adults with an initial body mass index (BMI) of: [4] [5] 30 kg/m 2 (obese), or [4] [5]
Bupropion, when used for treating long-term weight gain over six to twelve months, results in an average weight loss of 2.7 kilograms (6.0 lb) over placebo. [74] This is not much different from the weight loss produced by several other weight-loss medications such as sibutramine or orlistat . [ 74 ]
For example, a large-scale systematic review published in the journal Obesity Reviews in 2019 found that most studies of antidepressants and changes in body mass show an average weight increase of ...
In addition, about 15–30% of participants had weight measurements exactly at the 6-month, 1-year, and 2-year marks, and only 40% to 50% had weight measurements at one time point or more. This ...
Another review published in 2019 found that while the most popular medications used to treat depression caused weight gain, bupropion actually caused people to lose weight instead. Changes in the ...
Bupropion/zonisamide (former tentative brand name Empatic, Excalia) is an experimental combination of bupropion which was under development for the treatment of obesity. [1] [2] [3] Bupropion is a norepinephrine–dopamine reuptake inhibitor and nicotinic acetylcholine receptor antagonist, while zonisamide is an anticonvulsant acting as a sodium channel blocker, T-type calcium channel blocker ...
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109 S High St #100, Columbus, OH · Directions · (614) 224-4261