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Ondansetron, sold under the brand name Zofran among others, is a medication used to prevent nausea and vomiting caused by chemotherapy, radiation therapy, migraines, or surgery. [8] It is also effective for treating gastroenteritis. [9] [10] It can be given orally (by mouth), intramuscularly (injection into a muscle), or intravenously ...
Ondansetron was approved by the U.S. Food and Drug Administration in 1991, and has since become available in several other countries, including the UK, Ireland, Australia, Canada, France and Brazil. As of 2008, ondansetron and granisetron are the only 5-HT 3 antagonists available as a generic drug in the United States. Ondansetron may be given ...
Ondansetron; Palonosetron; Tropisetron; Other 5-HT 3 antagonists have been considered for use in the treatment of irritable bowel syndrome: Alosetron; Cilansetron; Also, the antidepressant mirtazapine acts as a 5-HT 3 antagonist.
Aprepitant has also been shown to increase the activity of the 5-HT 3 receptor antagonists ondansetron and the corticosteroid dexamethasone, which are also used to prevent nausea and vomiting caused by chemotherapy. [11] Netupitant has recently been approved by USFDA. It has also been marketed in combination with palonosetron.
Aprepitant is classified as an NK 1 antagonist because it blocks signals given off by NK 1 receptors.This, therefore, decreases the likelihood of vomiting in patients. NK 1 is a G protein-coupled receptor located in the central and peripheral nervous system.
The maximum semaglutide dose for weight loss is 2.4 milligrams (mg) per week. Your healthcare provider will start you on a lower weekly dose and gradually increase it over time.
Clonazepam ODT blister pack and tablet Etizest-1 MD (Etizest-brand 1mg-doskk etizolam mouth-dissolving (MD) blister pack and opened tablet. An orally disintegrating tablet or orally dissolving tablet (ODT) is a drug dosage form available for a limited range of over-the-counter (OTC) and prescription medications.
Sublingual tablets—tablets which easily melt in the mouth, dissolve rapidly and with little or no residue. Nitroglycerine tablets are an example, the anti-emetic ondansetron is another. Sublingual strips—similar to tablets in that they easily melt in the mouth and dissolve rapidly.
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