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The homogeneous pattern is seen when the condensed chromosomes and interphase chromatin stain. This pattern is associated with anti-dsDNA antibodies, antibodies to nucleosomal components, and anti-histone antibodies. There are two speckled patterns: fine and coarse.
HEp-2 cells provide a greater ability to differentiate patterns of ANA than animal sections, due to the large nuclei and high mitotic rate of the cell line. Upon incubation with serum containing anti-dsDNA antibodies and fluorescent labelled secondary antibodies, homogeneous staining of interphase nuclei and condensed chromosomal staining of ...
ANA screening yields positive results in many connective tissue disorders and other autoimmune diseases, and may occur in normal individuals. Subtypes of antinuclear antibodies include anti-Smith and anti-double stranded DNA ( anti-dsDNA ) antibodies (which are linked to SLE) and anti-histone antibodies (which are linked to drug-induced lupus).
Homogeneity and heterogeneity; only ' b ' is homogeneous Homogeneity and heterogeneity are concepts relating to the uniformity of a substance, process or image.A homogeneous feature is uniform in composition or character (i.e., color, shape, size, weight, height, distribution, texture, language, income, disease, temperature, radioactivity, architectural design, etc.); one that is heterogeneous ...
Consider the linear regression equation = +, =, …,, where the dependent random variable equals the deterministic variable times coefficient plus a random disturbance term that has mean zero. The disturbances are homoscedastic if the variance of ε i {\displaystyle \varepsilon _{i}} is a constant σ 2 {\displaystyle \sigma ^{2}} ; otherwise ...
PatA patterns the heterocysts along the filaments, and it is also important for cell division. PatS influences the heterocyst patterning by inhibiting heterocyst differentiation when a group of differentiating cells come together to form a pro- heterocyst (immature heterocyst). [5] Heterocyst maintenance is dependent on an enzyme called hetN.
Pattern I The scar presents T-cells and macrophages around blood vessels, with preservation of oligodendrocytes, but no signs of complement system activation. [59] Pattern II The scar presents T-cells and macrophages around blood vessels, with preservation of oligodendrocytes, as before, but also signs of complement system activation can be ...
It describes how patterns in nature, such as stripes and spirals, can arise naturally from a homogeneous, uniform state. The theory, which can be called a reaction–diffusion theory of morphogenesis, has become a basic model in theoretical biology. [2] Such patterns have come to be known as Turing patterns.