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A recent trial shows that people with depression experienced greater symptom relief after 6 months of treatment with psilocybin compared to escitalopram, a common SSRI.
Psilocybin therapy is the use of psilocybin (the psychoactive ingredient in psilocybin mushrooms) in treating a range of mental health conditions, such as depression, anxiety, addictions, [1] obsessive compulsive disorder (OCD), and psychosis. [2] It is one of several forms of psychedelic therapy under study.
These two studies are some of the first large controlled studies measuring the effects of psychedelic therapy on depression and anxiety in cancer patients. [66] Across clinician-ratings and self-ratings, the psychedelic treatment produced statistically significant lowered anxiety and depression, with sustenance for at least 6 months.
The discovery of antidepressive action of ketamine in 2000 [144] has been described as the single most important advance in the treatment of depression in more than 50 years. [61] [11] It has sparked interest in NMDA receptor antagonists for depression, [145] and has shifted the direction of antidepressant research and development. [146]
The main indication for SSRIs is major depressive disorder; however, they are frequently prescribed for anxiety disorders, such as social anxiety disorder, generalized anxiety disorder, panic disorder, obsessive–compulsive disorder (OCD), eating disorders, chronic pain, and, in some cases, for posttraumatic stress disorder (PTSD).
Winston Churchill is a famous example of someone who treated his depression by occupying himself with work and other productive activities. Out of office, Churchill was prone to depression (his "black dog") as he sensed his political talents being wasted and time passing him by – in all such times, writing provided the antidote. [182]
At higher-than-therapeutic doses, atropine and scopolamine cause CNS depression characterized by amnesia, fatigue, and reduction in rapid eye movement sleep. Scopolamine (Hyoscine) has anti-emetic activity and is, therefore, used to treat motion sickness. Antimuscarinics are also used as anti-parkinsonian drugs.
When Taylor Swift’s depression works the graveyard shift, she makes a playlist about it.. Swift, 34, partnered with Apple Music earlier this month to unveil five exclusive playlists featuring ...
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