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Lateral medullary syndrome is a neurological disorder causing a range of symptoms due to ischemia in the lateral part of the medulla oblongata in the brainstem.The ischemia is a result of a blockage most commonly in the vertebral artery or the posterior inferior cerebellar artery. [1]
A disrupted blood supply to posterior inferior cerebellar artery due to a thrombus or embolus can result in a stroke and lead to lateral medullary syndrome. Severe occlusion of this artery or to vertebral arteries could lead to Horner's Syndrome as well.
A blood vessel blockage (such as in a stroke) will injure the pyramidal tract, medial lemniscus, and the hypoglossal nucleus. This causes a syndrome called medial medullary syndrome. Lateral medullary syndrome can be caused by the blockage of either the posterior inferior cerebellar artery or of the vertebral arteries.
Medial medullary syndrome, also known as inferior alternating syndrome, hypoglossal alternating hemiplegia, lower alternating hemiplegia, [1] or Dejerine syndrome, [2] is a type of alternating hemiplegia characterized by a set of clinical features resulting from occlusion of the anterior spinal artery.
Right Horner's syndrome, right facial paresis, dysphagia, and paralysis of the right soft palate and ride side of the tongue were present. Cranial MRI showed a right hemi medullary infarct, and magnetic resonance angiography showered severe stenosis of the right vertebral artery.
Brain ischemia has been linked to a variety of diseases or abnormalities. Individuals with sickle cell anemia, compressed blood vessels, ventricular tachycardia, plaque buildup in the arteries, blood clots, extremely low blood pressure as a result of heart attack, and congenital heart defects have a higher predisposition to brain ischemia in comparison to the average population.
Cerebral infarction, also known as an ischemic stroke, is the pathologic process that results in an area of necrotic tissue in the brain (cerebral infarct). [1] In mid to high income countries, a stroke is the main reason for disability among people and the 2nd cause of death. [ 2 ]
Research is still needed in the area of cerebellar stroke management; however, several factors may lead to poor outcomes in individuals who have a cerebellar stroke. These factors include: Declining levels of consciousness; New signs of brainstem involvement; Progressing Hydrocephalus; Stroke to the midline of the cerebellum (a.k.a. the vermis) [4]