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Radiofrequency ablation has been used successfully on benign thyroid nodules for decades, most notably in Europe, South America and Korea. [citation needed] In the United States, the FDA approved the use of RFA techniques for thyroid nodules in 2018. Since then, professional guidelines reflect its use as a viable treatment modality for thyroid ...
Non-surgical, minimally invasive ultrasound-guided techniques are used for the treatment of large, symptomatic nodules. They include percutaneous ethanol injection, laser thermal ablation, radiofrequency ablation, high intensity focused ultrasound (HIFU), and percutaneous microwave ablation. [30]
Medical applications of radio frequency (RF) energy, in the form of electromagnetic waves (radio waves) or electrical currents, have existed for over 125 years, [1] and now include diathermy, hyperthermy treatment of cancer, electrosurgery scalpels used to cut and cauterize in operations, and radiofrequency ablation. [2]
1990 – Radiofrequency ablation (RFA) technique for liver tumors. 1990s – Treatment of bone and kidney tumors by embolization. 1990s – RFA for soft tissue tumors, i.e., bone, breast, kidney, lung and liver cancer. 1997 – Intra-arterial delivery of tumor-killing viruses and gene therapy vectors to the liver.
Various local ablation therapies exist to induce necrosis of tumor cells and release tumor antigens to stimulate an immunological response. These ablation therapies can be combined with a systemic immunotherapy: Thermal ablation – local thermal ablation of tumor: Cryoablation; Radiofrequency ablation; High-intensity focused ultrasound ablation
Thyroid cancer accounts for less than 1% of cancer cases and deaths in the UK. Around 2,700 people were diagnosed with thyroid cancer in the UK in 2011, and around 370 people died from the disease in 2012. [69] However, in South Korea, thyroid cancer was the 5th most prevalent cancer, which accounted for 7.7% of new cancer cases in 2020. [70]
IRE has also been investigated in ex-vivo human eye models for treatment of uveal melanoma [103] and in thyroid cancer. [ 104 ] Successful ablations in animal tumor models have been conducted for lung, [ 105 ] [ 106 ] brain, [ 107 ] [ 108 ] heart, [ 109 ] skin, [ 110 ] [ 111 ] bone, [ 112 ] [ 113 ] head and neck cancer, [ 114 ] and blood vessels.
Radiosurgery is surgery using radiation, [1] that is, the destruction of precisely selected areas of tissue using ionizing radiation rather than excision with a blade. Like other forms of radiation therapy (also called radiotherapy), it is usually used to treat cancer.
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