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Less melanin translates to less pigment, therefore turning your hair gray—FYI, this means gray hair has less pigment, and white hair has a total lack of pigment. While most people will start to ...
They have more volume in the middle of the face compared to the forehead and chin. "There tends to be less contour between the cheek and jawline or the cheek and the temples," says Dr. Tripathi.
As you age, you produce less melanin, resulting in gradual graying. Genetics will affect when this starts, but generally speaking, most people start to see gray hairs in their 30s and early 40s.
Neuromelanin (NM) is a dark pigment found in the brain which is structurally related to melanin. It is a polymer of 5,6-dihydroxyindole monomers. [1] Neuromelanin is found in large quantities in catecholaminergic cells of the substantia nigra pars compacta and locus coeruleus, giving a dark color to the structures. [2]
Smoking results in generation of huge amount of reactive oxygen species leading to increased oxidative stress culminating into damage to melanin producing cells, melanocytes. [ 4 ] [ 5 ] Prolonged exposure to ultraviolet rays is considered to initiate similar processes in hair follicles resulting in premature greying of hair.
Melanosomes, which are organelles containing melanin, must be transported and increased during hyperpigmentation and tanning, while they shrink during hypopigmentation. [4] Skin pigmentation is frequently caused by sun exposure. To protect itself against UV radiation from the sun, the body makes more melanin. As a result, the skin may become ...
It is caused by melanocyte or melanin depletion, or a decrease in the amino acid tyrosine, which is used by melanocytes to make melanin. [2] Some common genetic causes include mutations in the tyrosinase gene or OCA2 gene. [3] [4] As melanin pigments tend to be in the skin, eye, and hair, these are the commonly affected areas in those with ...
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