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  2. Management of HIV/AIDS - Wikipedia

    en.wikipedia.org/wiki/Management_of_HIV/AIDS

    The study was stopped early (after 1.7 years) for ethical reasons when it became clear that antiviral treatment provided significant protection. Of the 28 couples where cross-infection had occurred, all but one had taken place in the control group, consistent with a 96% reduction in risk of transmission while on ART.

  3. Reverse-transcriptase inhibitor - Wikipedia

    en.wikipedia.org/wiki/Reverse-transcriptase...

    This drug has been discontinued by the manufacturer. Stavudine, also called d4T, has trade names Zerit and Zerit XR. Lamivudine, also called 3TC, has the trade name Zeffix and Epivir. It is approved for the treatment of both HIV and hepatitis B. Abacavir, also called ABC, has the trade name Ziagen, is an analog of guanosine.

  4. Antiviral drug - Wikipedia

    en.wikipedia.org/wiki/Antiviral_drug

    Antiviral drugs are a class of antimicrobials, a larger group which also includes antibiotic (also termed antibacterial), antifungal and antiparasitic drugs, [3] or antiviral drugs based on monoclonal antibodies. [4] Most antivirals are considered relatively harmless to the host, and therefore can be used to treat infections.

  5. Protease inhibitor (pharmacology) - Wikipedia

    en.wikipedia.org/wiki/Protease_inhibitor...

    A drug combination targeting SARS-CoV-2, Paxlovid, was approved in December 2021 to treat COVID-19. [12] It is a combination of nirmatrelvir , a protease inhibitor targeted to the SARS-CoV-2 3C-like protease , and ritonavir, which inhibits the metabolism of nirmatrelvir, thereby prolonging its effect.

  6. Nirmatrelvir/ritonavir - Wikipedia

    en.wikipedia.org/wiki/Nirmatrelvir/ritonavir

    The primary data supporting the US Food and Drug Administration (FDA) emergency use authorization for nirmatrelvir/ritonavir were from the EPIC-HR trial, a randomized, double-blind, placebo-controlled clinical trial studying nirmatrelvir/ritonavir for the treatment of non-hospitalized symptomatic adults with a laboratory-confirmed diagnosis of ...

  7. List of antiviral drugs - Wikipedia

    en.wikipedia.org/wiki/List_of_antiviral_drugs

    List of Antiviral Drugs Antiviral Use Manufacturer Component Type Year approved Abacavir: HIV: ViiV Healthcare: Nucleoside analogue reverse transcriptase inhibitor (NRTI) 1998 Acyclovir (Aciclovir) Herpes Simplex, chickenpox, [2] varicella zoster virus: GSK: guanosine analogue RTI 1981 Adefovir: Hepatitis B [3] Gilead Sciences RTI 2002 , 2003 ...

  8. Targeted drug delivery - Wikipedia

    en.wikipedia.org/wiki/Targeted_drug_delivery

    The conventional drug delivery system is the absorption of the drug across a biological membrane, whereas the targeted release system releases the drug in a dosage form. The advantages to the targeted release system is the reduction in the frequency of the dosages taken by the patient, having a more uniform effect of the drug, reduction of drug ...

  9. Dextran drug delivery systems - Wikipedia

    en.wikipedia.org/wiki/Dextran_drug_delivery_systems

    Dextran conjugates are also utilized in nanoparticle drug delivery system formulations. Nanoparticles composted of dextran and stearic acid with a polyethylene glycol (PEG) coating can be loaded with antiviral drugs and be effectively internalized by cells. This nanosystem has the advantages of providing protection against immune responses and ...