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  2. Corepressor - Wikipedia

    en.wikipedia.org/wiki/Corepressor

    In genetics and molecular biology, a corepressor is a molecule that represses the expression of genes. [1] In prokaryotes, corepressors are small molecules whereas in eukaryotes, corepressors are proteins. A corepressor does not directly bind to DNA, but instead indirectly regulates gene expression by binding to repressors.

  3. Transcription coregulator - Wikipedia

    en.wikipedia.org/wiki/Transcription_coregulator

    Corepressor proteins also bind to the surface of the ligand binding domain of nuclear receptors, but through a LXXXIXXX(I/L) motif of amino acids (where L = leucine, I = isoleucine and X = any amino acid). [7] In addition, compressors bind preferentially to the apo (ligand free) form of the nuclear receptor (or possibly antagonist bound receptor).

  4. Nuclear receptor co-repressor 1 - Wikipedia

    en.wikipedia.org/.../Nuclear_receptor_co-repressor_1

    20185 Ensembl ENSG00000141027 ENSMUSG00000018501 UniProt O75376 Q60974 RefSeq (mRNA) NM_001190438 NM_001190440 NM_006311 NM_001252313 NM_011308 NM_177229 RefSeq (protein) NP_001177367 NP_001177369 NP_006302 n/a Location (UCSC) Chr 17: 16.03 – 16.22 Mb Chr 11: 62.21 – 62.35 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse The nuclear receptor co-repressor 1 also known as thyroid ...

  5. RCOR1 - Wikipedia

    en.wikipedia.org/wiki/RCOR1

    23186 217864 Ensembl ENSG00000089902 ENSMUSG00000037896 UniProt Q9UKL0 Q8CFE3 RefSeq (mRNA) NM_015156 NM_198023 RefSeq (protein) NP_055971 NP_932140 Location (UCSC) Chr 14: 102.59 – 102.73 Mb Chr 12: 111.01 – 111.08 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse REST corepressor 1 also known as CoREST is a protein that in humans is encoded by the RCOR1 gene. Function This gene ...

  6. Nuclear receptor coregulators - Wikipedia

    en.wikipedia.org/wiki/Nuclear_receptor_coregulators

    The ability of nuclear receptors to alternate between activation and repression in response to specific molecular cues, is now known to be attributable in large part to a diverse group of cellular factors, collectively termed coregulators and including coactivators and corepressors.

  7. DRAP1 - Wikipedia

    en.wikipedia.org/wiki/DRAP1

    Dr1-associated corepressor is a protein that in humans is encoded by the DRAP1 gene. [ 5 ] [ 6 ] Transcriptional repression is a general mechanism for regulating transcriptional initiation in organisms ranging from yeast to humans.

  8. 10 Best Conditioning Exercises for Beginners To Do at Home - AOL

    www.aol.com/lifestyle/10-best-conditioning...

    Jumping rope is a fantastic cardiovascular exercise that improves coordination, agility, and lower-body strength. Beginners can start with an imaginary jump rope if they don't have a physical one.

  9. Silencer (genetics) - Wikipedia

    en.wikipedia.org/wiki/Silencer_(genetics)

    The 3' untranslated region of mRNA labeled 3' UTR. Normally about 700 nucleotides in human mRNA. A silencer is a sequence-specific element that induces a negative effect on the transcription of its particular gene. There are many positions in which a silencer element can be located in DNA.