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Using FISH for diagnostic purposes has found its purpose when immediate species identification is needed, specifically for the investigation of blood cultures for which FISH is a cheap and easy technique for preliminary rapid diagnosis. [30] FISH can also be used to compare the genomes of two biological species, to deduce evolutionary ...
The theoretical reason for this is the undecidability of the Halting Problem: there cannot exist some algorithm which determines whether any given program stops after finitely many computation steps. In practice one fails to show termination (or non-termination) because every algorithm works with a finite set of methods being able to extract ...
Chromosome combing (also known as molecular combing or DNA combing) [1] is a technique used to produce an array of uniformly stretched DNA that is then highly suitable for nucleic acid hybridization studies such as fluorescent in situ hybridisation (FISH) which benefit from the uniformity of stretching, the easy access to the hybridisation target sequences, [2] and the resolution offered by ...
Quantitative Fluorescent in situ hybridization (Q-FISH) is a cytogenetic technique based on the traditional FISH methodology. In Q-FISH, the technique uses labelled (Cy3 or FITC) synthetic DNA mimics called peptide nucleic acid (PNA) oligonucleotides to quantify target sequences in chromosomal DNA using fluorescent microscopy and analysis software.
Flow-FISH was first published in 1998 by Rufer et al. [11] as a modification of another technique for analyzing telomere length, Q-FISH, that employs peptide nucleic acid probes [12] of a 3'-CCCTAACCCTAACCCTAA-5' sequence labeled with a fluorescin fluorophore to stain telomeric repeats on prepared metaphase spreads of cells that have been treated with colcemid, hypotonic shock, and fixation to ...
Flowchart of using successive subtractions to find the greatest common divisor of number r and s. In mathematics and computer science, an algorithm (/ ˈ æ l ɡ ə r ɪ ð əm / ⓘ) is a finite sequence of mathematically rigorous instructions, typically used to solve a class of specific problems or to perform a computation. [1]
Computer programming or coding is the composition of sequences of instructions, called programs, that computers can follow to perform tasks. [1] [2] It involves designing and implementing algorithms, step-by-step specifications of procedures, by writing code in one or more programming languages.
Simple computations in all individuals (i.e. fish) Various means of storing information (i.e. weights of fish and school barycenter) Local computations (i.e. swimming is composed of distinct components) Low communications between neighboring individuals (i.e. fish are to think local but also be socially aware)