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  2. This Chronic Skin Condition Is A Common Cause Of Dark ... - AOL

    www.aol.com/lifestyle/chronic-skin-condition...

    In short, melasma is a chronic skin condition that appears as darkened areas on the face due to an overproduction of melanin, says Gina Charles, MO, a family physician specializing in skincare. It ...

  3. Why Is Your Skin A Wreck? You Could Be Going Through ... - AOL

    www.aol.com/why-skin-wreck-could-going-170100994...

    Estrogen also rises during pregnancy, and that, combined with progesterone, can contribute to the formation of melasma, which appears as dark brown spots or patches. ... Treatment options are ...

  4. Dealing with Weird Dark Patches? Melasma May Be the ... - AOL

    www.aol.com/dealing-weird-dark-patches-melasma...

    If over-the-counter products aren’t helping your melasma, visit your dermatologist, who can prescribe oral and topical treatments such as oral tranexamic acid or skin-lightening creams, Dr ...

  5. Melasma - Wikipedia

    en.wikipedia.org/wiki/Melasma

    The symptoms of melasma are dark, irregular, well-demarcated, hyperpigmented macules to patches. These patches often develop gradually over time. Melasma does not cause any other symptoms beyond the cosmetic discoloration. [4] Patches can vary in size from 0.5 cm (0.2 in) to larger than 10 cm (4 in) depending on the person.

  6. Hyperpigmentation - Wikipedia

    en.wikipedia.org/wiki/Hyperpigmentation

    Melasma, also known as 'chloasma' or the “mask of pregnancy,” when it occurs in pregnant women.— It is a common skin problem that causes dark discolored patchy hyperpigmentation. It typically occurs on the face and is symmetrical, with matching marks on both sides of the face.

  7. Estradiol cypionate - Wikipedia

    en.wikipedia.org/wiki/Estradiol_cypionate

    Examples of such side effects include breast tenderness and enlargement, nausea, vomiting, bloating, edema, headache, migraine, and melasma. [54] [55] High-dose estrogen therapy with estradiol cypionate injections may also cause an increased risk of thromboembolism, changes in blood lipid profile, increased insulin resistance, and increased ...

  8. 11 dermatologist-approved melasma treatments of 2023

    www.aol.com/news/11-dermatologist-approved...

    Azelaic acid, which this product is formulated with, is a great over-the-counter (and pregnancy-safe) alternative to prescription hydroquinone, an old-school treatment for melasma. “[Azelaic ...

  9. Estrogen and neurodegenerative diseases - Wikipedia

    en.wikipedia.org/wiki/Estrogen_and...

    By using a cell line that contains high levels of estrogen receptors, scientists found that treatment with physiological concentrations of 17 beta-estradiol is associated with accumulation in the conditioned medium of an amino-terminal cleavage product of APP (soluble APP or protease nexin-2), indicative of non-amyloidogenic processing.

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