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Both Pfizer and Moderna’s Omicron boosters are "bivalent" vaccines, meaning they protect against Omicron BA.5 and BA.4 subvariants and the original SARS-CoV-2 virus. "The goal of a COVID vaccine ...
Two shots of COVID-19 vaccine without an additional booster offer essentially no lasting protection against infection with Omicron, and a coronavirus infection is as effective as a recent booster ...
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In June 2022, Pfizer and Moderna developed bivalent vaccines to protect against the SARS-CoV-2 wild-type and the Omicron variant. The bivalent vaccines are well-tolerated and offer immunity to Omicron superior to previous mRNA vaccines. [268] In September 2022, the United States Food and Drug Administration (FDA) authorized the bivalent vaccines.
There are no human data yet on the new Omicron booster, but past research hints at an answer.
In August 2022, the "Pfizer-BioNTech COVID-19 Vaccine, Bivalent (Original and Omicron BA.4/BA.5)" (in short: "COVID-19 Vaccine, Bivalent") received an emergency use authorization from the US Food and Drug Administration (FDA) for use as a booster dose in individuals aged twelve years of age and older.
It concerns both human and animal vaccines. Although the emergence of a number of vaccine resistant pathogens has been well documented, this phenomenon is nevertheless much more rare and less of a concern than antimicrobial resistance. Vaccine resistance may be considered a special case of immune evasion, from the immunity conferred by the vaccine.
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