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Rifampicin can reduce the efficacy of birth control pills or other hormonal contraception by its induction of the cytochrome P450 system, to the extent that unintended pregnancies have occurred in women who use oral contraceptives and took rifampicin even for very short courses (for example, as prophylaxis against exposure to bacterial meningitis).
[73] [74] Some of the people acutely ill with COVID-19 experience deterioration of their lungs and acute respiratory distress syndrome (ARDS) and/or respiratory failure. Due to the high risk of death, urgent respiratory support including mechanical ventilation is often required in these people. [ 75 ]
Lepetit introduced Rifampicin, an orally active rifamycin, in 1966. [16] Rifabutin, a derivative of rifamycin S, was invented by Italian drug manufacturer Achifar in 1975 and came onto the US market in 1992. [16] Hoechst Marion Roussel (now part of Aventis) introduced rifapentine to the US market in 1998, with Achifar having synthesized it in ...
One of the most notable scientific papers that first popularized hydroxychloroquine as a COVID-19 treatment was retracted from its journal due to ethical and methodological issues. Retractions in ...
Around the globe, a new strain of COVID-19 is spreading exponentially. The COVID-19 XEC variant is derived from Omicron strains KS.1.1 and KP.3.3, says Dr. Francesca Torriani , MD, an infectious ...
Coronavirus vaccines require two shots to be fully effective, and it can take up to a few weeks for vaccinated people to develop immunity. An emergency-room doctor tested positive for coronavirus ...
One antiviral strategy is to interfere with the ability of a virus to infiltrate a target cell. The virus must go through a sequence of steps to do this, beginning with binding to a specific "receptor" molecule on the surface of the host cell and ending with the virus "uncoating" inside the cell and releasing its contents. Viruses that have a ...
The many people who have recently had COVID-19 may wait for as long as three months to get vaccinated, according to the CDC, as an infection in many cases imparts strong, if fleeting, protection ...