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Crack cocaine. The Fair Sentencing Act of 2010 (Pub. L. 111–220 (text)) was an Act of Congress that was signed into federal law by United States President Barack Obama on August 3, 2010, that reduces the disparity between the amount of crack cocaine and powder cocaine needed to trigger certain federal criminal penalties from a 100:1 weight ratio to an 18:1 weight ratio [1] and eliminated the ...
Two grams of crack cocaine. Crack cocaine, commonly known simply as crack, and also known as rock, is a free base form of the stimulant cocaine that can be smoked. Crack offers a short, intense high to smokers. The Manual of Adolescent Substance Abuse Treatment calls it the most addictive form of cocaine. [1]
Drug liking is a measure of the pleasurable (hedonic) experience when a person consumes drugs. [1] It is commonly used to study the misuse liability of drugs. [2] [3] [4] Drug liking is often measured using unipolar and bipolar visual analogue scales (VAS), such as the Drug Liking VAS, the High VAS, the Take Drug Again (TDA) VAS, and the Overall Drug Liking (ODL) VAS.
In an analysis of the drug development costs for 98 companies over a decade, the average cost per drug developed and approved by a single-drug company was $350 million. [3] But for companies that approved between eight and 13 drugs over 10 years, the cost per drug went as high as $5.5 billion. [3]
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Not all medications have a fixed relationship on this scale. Methadone is different from most opioids because its potency can vary depending on how long it is taken. Acute use (1–3 days) yields a potency about 1.5× stronger than that of morphine and chronic use (7 days+) yields a potency about 2.5 to 5× that of morphine.
This is a list of states (and some territories) by the annual prevalence of cocaine use as percentage of the population aged 15–64 (unless otherwise indicated). [1] published by the United Nations Office on Drugs and Crime (UNODC). The indicator is the "annual prevalence" rate which is the percentage of the youth and adult population who have ...
English: A rational scale to assess the harm of drugs. Data source is the March 24, 2007 article: Nutt, David, Leslie A King, William Saulsbury, Colin Blakemore. "Development of a rational scale to assess the harm of drugs of potential misuse" The Lancet 2007; 369:1047-1053.