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Myelin is formed by oligodendrocytes in the central nervous system and Schwann cells in the peripheral nervous system.Therefore, the first stage of myelinogenesis is often defined as the differentiation of oligodendrocyte progenitor cells (OPCs) or Schwann cell progenitors into their mature counterparts, [4] followed by myelin formation around axons.
The development of the nervous system in humans, or neural development, or neurodevelopment involves the studies of embryology, developmental biology, and neuroscience.These describe the cellular and molecular mechanisms by which the complex nervous system forms in humans, develops during prenatal development, and continues to develop postnatally.
For example, mice undergo cortical neurogenesis from about embryonic day (post-conceptional day) (E)11 to E17, and are born at about E19.5. [9] Ferrets are born at E42, although their period of cortical neurogenesis does not end until a few days after birth. [10]
The process of generating myelin is called myelination or myelinogenesis. In the CNS, oligodendrocyte progenitor cells (OPCs) differentiate into mature oligodendrocytes, which form myelin. In humans, myelination begins early in the 3rd trimester, [ 11 ] although only little myelin is present in either the CNS or the PNS at the time of birth.
The white matter in preterm born children is particularly vulnerable during the third trimester of pregnancy when white matter developing takes place and the myelination process starts around 30 weeks of gestational age. [3]
The preplate is the first stage in corticogenesis prior to the development of the cortical plate. The preplate is located between the pia mater and the ventricular zone. . According to current knowledge, the preplate contains the first-born or pioneer neur
Natural Born Killers would appear in theaters in the summer of 1994, just as the twenty-four-hour news cycle was tightening its stranglehold on American life. CNN came on the air June 1, 1980, and ...
The first point is at 12–17 days into embryo development, and the second is between 16 and 30 days after the rat has been born. Baby rats, from mothers fed a diet lacking in choline during these two periods of pregnancy, have poorer memory function than baby rats from mothers who received choline. Choline, when given during these critical ...