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Prevalence of vitamin A deficiency, 1995-2005. Vitamin A deficiency (VAD) or hypovitaminosis A is a lack of vitamin A in blood and tissues. [1] It is common in poorer countries, especially among children and women of reproductive age, but is rarely seen in more developed countries. [1]
Xerophthalmia (from Ancient Greek xērós (ξηρός) meaning "dry" and ophthalmos (οφθαλμός) meaning "eye") is a medical condition in which the eye fails to produce tears. It may be caused by vitamin A deficiency, [1] which is sometimes used to describe that condition, although there may be other causes.
Vitamin A deficiency-caused night blindness is a reversible difficulty for the eyes to adjust to dim light. It is common in young children who have a diet inadequate in retinol and β-carotene. It is common in young children who have a diet inadequate in retinol and β-carotene.
Bitot's spots are the buildup of keratin located superficially in the conjunctiva of human's eyes. They can be oval, triangular or irregular in shape. The spots are a sign of vitamin A deficiency and associated with drying of the cornea. In 1863, the French physician Pierre Bitot (1822–1888) first described these spots. [1]
This vitamin deficiency blinds hundreds of thousands of kids each year, and is a preventable cause of childhood blindness. Since vitamin A is required for rhodopsin, the photosensitive pigment in the retinol rods, its deficiency can lead to night blindness. [8]
Keratomalacia is an eye disorder that results from vitamin A deficiency. Vitamin A is required to maintain specialized epithelia (such as in the cornea and conjunctiva).. The precise mechanism is still not known, but vitamin A is necessary for the maintenance of the specialized epithelial surfaces of the body.
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