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Postherpetic neuralgia is the most common long-term complication of herpes zoster, and occurs in approximately 20% of patients with shingles. [2] Risk factors for PHN include older age, severe prodrome or rash , severe acute zoster pain, ophthalmic involvement, immunosuppression , and chronic conditions such as diabetes mellitus and lupus . [ 1 ]
The short- and long-term pain caused by shingles outbreaks originates from inflammation of affected nerves due to the widespread growth of the virus in those areas. [47] As with chickenpox and other forms of alpha-herpesvirus infection, direct contact with an active rash can spread the virus to a person who lacks immunity to it.
Shingles may start as an itchy, tingling or burning pain on one side of the face or body followed by a blistering, painful red rash two or three days later. Causes of shingles
Aciclovir, also known as acyclovir, [4] is an antiviral medication. [5] It is primarily used for the treatment of herpes simplex virus infections, chickenpox, and shingles. [6]
Shingles, also called zoster or herpes zoster, is a viral infection that affects the nerves.
Back pain that lasts more than a few weeks should be investigated and discussed with your doctor, says Dr. Shah. “Other signs that occur alongside back pain require more urgent evaluation ...
A zoster vaccine is a vaccine that reduces the incidence of herpes zoster (shingles), a disease caused by reactivation of the varicella zoster virus, which is also responsible for chickenpox. [8] Shingles provokes a painful rash with blisters, and can be followed by chronic pain ( postherpetic neuralgia ), as well as other complications.
In 10–15% of cases the pain persists more than three months, a chronic and often disabling condition known as postherpetic neuralgia. Other serious complications of varicella zoster infection include Mollaret's meningitis , zoster multiplex, and inflammation of arteries in the brain leading to stroke , [ 11 ] myelitis, herpes ophthalmicus, or ...
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