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MCF-7 is a breast cancer cell line isolated in 1970 from a 69-year-old White woman. [1] MCF-7 is the acronym of Michigan Cancer Foundation-7 , referring to the institute in Detroit where the cell line was established in 1973 by Herbert Soule and co-workers. [ 2 ]
Originally the cell line was named MCF-7/ADR-RES; it was renamed together with the change in classification. [8] Two brain cancer cell lines, SNB-19 and U251, were discovered to come from the same person. [9] This makes a mixup likely. A 61st cell line, MDA-N, has been confirmed to being derived from the misclassified MDA-MB-435 cell line. [7]
The E-SCREEN cell proliferation assay is performed with the human MCF-7 breast cancer cell line, an established estrogenic cell line that endogenously expresses ERα. [ 1 ] [ 3 ] [ 4 ] Human MCF-7 are cultivated in Dulbecco’s modified Eagle’s medium (DMEM) with fetal bovine serum (FBS) and phenol red as buffer tracer (culture medium), at 37 ...
2 sisters, 7 years apart in age, also receive heart transplants 7 years apart. Shardaa Gray. Updated December 18, 2024 at 5:18 AM. CBS.
Chemical Structure of Globo H [4]. Defined by the monoclonal antibody MBr1, Globo H has been isolated from breast cancer cell line MCF-7, and its structure has been determined through several analyses, including NMR spectroscopy and methylation analysis. [5]
Itaconate has been reported to increase succinate levels in a wide variety of cells including cultured mouse RAW264.7 macrophages, macrophages differentiated from human monocytes, [37] Huh7 human liver carcinoma cells, human MCF-7 breast cancer cells, human A549 lung adenocarcinoma cells, and the brain neurons and astrocytes generated from rat ...
WASHINGTON (Reuters) -A U.S. Justice Department watchdog report released on Thursday debunked claims by far-right conspiracy theorists who falsely alleged that FBI operatives were secretly ...
December 17, 2024 at 7:41 PM At 84 years old, Evelyn Paternostro spends her days working part time as a cashier at Dollar Tree. For decades, she dedicated her life to education, serving as a ...
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