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Microbial metabolism is the means by which a microbe obtains the energy and nutrients (e.g. carbon) it needs to live and reproduce.Microbes use many different types of metabolic strategies and species can often be differentiated from each other based on metabolic characteristics.
Venn diagram showing pharmacomicrobiomics as a sub-field of genomics, microbiology, and pharmacology. Pharmacomicrobiomics, proposed by Prof. Marco Candela for the ERC-2009-StG project call (proposal n. 242860, titled "PharmacoMICROBIOMICS, study of the microbiome determinants of the different drug responses between individuals"), and publicly coined for the first time in 2010 by Rizkallah et ...
During a pre clinical model, Eggerthella lenta was found to reduce amino acids such as arginine, citrulline and tryptophan metabolites to levels found in older persons and can trigger autoimmune responses before the onset of the clinical symptoms of rheumatoid arthritis in which the immune system produces autoantibodies that mistakenly target ...
Carbon catabolite repression, or simply catabolite repression, is an important part of global control system of various bacteria and other microorganisms. Catabolite repression allows microorganisms to adapt quickly to a preferred (rapidly metabolizable) carbon and energy source first.
may cause lifestyle-related diseases. These current nutritional crises have led to the development of low-calorie sugar substitutes. Various artiļ¬cial sweeteners have been developed to date and are widely used in food industrial products, such as soft drinks and confectioneries. Typical examples of sweet substances include saccharides, such
Macrophage polarization is a process by which macrophages adopt different functional programs in response to the signals from their microenvironment. This ability is connected to their multiple roles in the organism: they are powerful effector cells of the innate immune system, but also important in removal of cellular debris, embryonic development and tissue repair.
Physical exercise has a positive effect on the immune system and depending on the frequency and intensity, the pathogenic effects of diseases caused by bacteria and viruses are moderated. [103] Immediately after intense exercise there is a transient immunodepression, where the number of circulating lymphocytes decreases and antibody production ...
[1] [2] [3] Metabolic gene clusters are common features of bacterial [4] and most fungal [5] genomes. They are less often found in other [ 6 ] organisms. They are most widely known for producing secondary metabolites , the source or basis of most pharmaceutical compounds, natural toxins , chemical communication, and chemical warfare between ...