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Endometrial carcinoma is surgically staged using the FIGO cancer staging system. The 2009 FIGO staging system is commonly used. There is an updated 2023 FIGO staging system, but it is not yet universally adopted. [64] [65] The 2009 FIGO staging system is as follows: [66] [67]
It is an uncommon form of endometrial cancer that typically arises in postmenopausal women. It is typically diagnosed on endometrial biopsy, prompted by post-menopausal bleeding. Unlike the more common low-grade endometrioid endometrial adenocarcinoma, uterine serous carcinoma does not develop from endometrial hyperplasia and is not hormone ...
Endometrial cancer forms from the lining of the uterus, and uterine sarcoma forms from the muscles or support tissue of the uterus. [1] [2] Endometrial cancer accounts for approximately 90% of all uterine cancers in the United States. [6] Symptoms of endometrial cancer include changes in vaginal bleeding or pain in the pelvis. [1]
Uterine clear-cell carcinoma is staged like other forms of endometrial carcinoma at time of surgery using the International Federation of Gynecology and Obstetrics (FIGO) cancer staging system 2009. [4] IA Tumor confined to the uterus, no or < 1 ⁄ 2 myometrial invasion IB Tumor confined to the uterus, > 1 ⁄ 2 myometrial invasion
In 2011 FIGO recognized two systems designed to aid research, education, and clinical care of women with abnormal uterine bleeding (AUB) in the reproductive years. This page is a summary of the systems and their use in contemporary gynecology. FIGO System 1.
Unlike the more common low-grade endometrioid endometrial adenocarcinoma, uterine serous carcinoma does not develop from endometrial hyperplasia and is not hormone-sensitive. It arises in the setting of endometrial atrophy and is classified as a type II endometrial cancer. [6]
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Histopathology of a pelvic lymph node in a patient with endometrial adenocarcinoma (FIGO grade 1): - Left panel shows H&E staining and low magnification, where any presence of small metastases is hard to see. - Middle panel shows immunohistochemistry for CK AE1/AE3, which highlights even small tumor nests.
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