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Prucalopride, sold under brand names Resolor and Motegrity among others, is a medication acting as a selective, high affinity 5-HT 4 receptor agonist [4] which targets the impaired motility associated with chronic constipation, thus normalizing bowel movements.
It is available as a generic medication. [1] [6] In 2022, it was the 280th most commonly prescribed medication in the United States, with more than 600,000 prescriptions. [9] [10] In 2022, the combination with docusate was the 261st most commonly prescribed medication in the United States, with more than 1 million prescriptions.
These drugs inhibit dopamine and acetylcholine esterase enzyme and have a gastrokinetic effect. [3] Itopride is indicated for the treatment of functional dyspepsia and other gastrointestinal conditions. [4] It is a combined D 2 receptor antagonist and acetylcholinesterase inhibitor. [5] [6] Itopride is the dimethoxy analog of trimethobenzamide.
Updated January 10, 2025 at 10:30 AM When it comes to managing mild pain at home, there’s a strong probability you’ve already got a few types of OTC anti-inflammatories stocked in your ...
The WHO Model List of Essential Medicines for Children (aka Essential Medicines List for Children [1] or EMLc [1]), published by the World Health Organization (WHO), contains the medications considered to be most effective and safe in children up to twelve years of age to meet the most important needs in a health system. [2] [3]
Functional constipation: This typically happens when kids hold back bowel movements or after they have a gastrointestinal infection. Many children with constipation have functional constipation ...
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