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After filtration occurs, the blood moves through a small network of venules that converge into interlobular veins. As with the arteriole distribution, the veins follow the same pattern: the interlobular provide blood to the arcuate veins then back to the interlobar veins, which come to form the renal vein exiting the kidney for transfusion for ...
A healthy adult has 1 to 1.5 million nephrons in each kidney. [1]: 22 Blood is filtered as it passes through three layers: the endothelial cells of the capillary wall, its basement membrane, and between the podocyte foot processes of the lining of the capsule.
The glomerulus and its surrounding Bowman's capsule constitute a renal corpuscle, the basic filtration unit of the kidney. [2] The rate at which blood is filtered through all of the glomeruli, and thus the measure of the overall kidney function, is the glomerular filtration rate.
The interlobar arteries then supply blood to the arcuate arteries that run through the boundary of the cortex and the medulla. Each arcuate artery supplies several interlobular arteries that feed into the afferent arterioles that supply the glomeruli. Blood drains from the kidneys, ultimately into the inferior vena cava.
When renal blood flow is reduced (indicating hypotension) or there is a decrease in sodium or chloride ion concentration, the macula densa of the distal tubule releases prostaglandins (mainly PGI2 and PGE2) and nitric oxide, which cause the juxtaglomerular cells lining the afferent arterioles to release renin, activating the renin–angiotensin–aldosterone system, to increase blood pressure ...
This blood leaves the glomerulus via the efferent arteriole, which supplies the peritubular capillaries. The higher osmolarity of the blood in the peritubular capillaries creates an osmotic pressure which causes the uptake of water. Other ions can be taken up by the peritubular capillaries via solvent drag. Water is also driven into the ...
The renal medulla (Latin: medulla renis 'marrow of the kidney') is the innermost part of the kidney. The renal medulla is split up into a number of sections, known as the renal pyramids. Blood enters into the kidney via the renal artery, which then splits up to form the segmental arteries which then branch to form interlobar arteries.
In multilobar kidneys, the pyramids are separated from each other by dipped into the kidney areas of cortical tissue known as the renal columns. [61] Blood enters the kidney through the renal artery, which in the multilobar kidney then branches in the region of the renal pelvis into large interlobar arteries that pass through the renal columns.