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Adenoviral keratoconjunctivitis, also known as epidemic keratoconjunctivitis, is a contagious eye infection, a type of adenovirus disease caused by adenoviruses. [1] It typically presents as a conjunctivitis with a sudden onset of a painful red eye, watery discharge and feeling that something is in the eye. [ 3 ]
Adenovirus infection can also cause adenoviral keratoconjunctivitis. [5] Typically one eye is affected after an incubation period of up to a week. [5] The eye becomes itchy, painful, burning and reddish and lymphadenopathy may be felt by the ear nearest the affected eye. [5] The symptoms may last around 10 days to three weeks. [5]
Keratoconjunctivitis is a term used to describe inflammation of both the cornea (the clear, front part of the eye) and the conjunctiva (the thin, transparent membrane covering the white part of the eye and lining the inside of the eyelids). This condition can have various causes, and its presentation may vary depending on the underlying factors.
Herpetic keratoconjunctivitis, caused by herpes simplex viruses, can be serious and requires treatment with aciclovir. Acute hemorrhagic conjunctivitis is a highly contagious disease caused by one of two enteroviruses , enterovirus 70 and coxsackievirus A24.
Nummular Keratitis, a feature of the chronic phase of adenoviral keratoconjunctivitis. Nummular keratitis is a feature of viral keratoconjunctivitis.It is a common feature of adenoviral keratoconjunctivitis (an ocular adenovirus infection), [1] as well as approximately 1/3rd of cases of Herpes Zoster Ophthalmicus infections.
Ciclosporin is indicated to treat and prevent graft-versus-host disease in bone marrow transplantation and to prevent rejection of kidney, heart, and liver transplants. [8] [7] It is also approved in the US for treating of rheumatoid arthritis and psoriasis, persistent nummular keratitis following adenoviral keratoconjunctivitis, [25] [7] and as eye drops for treating dry eyes caused by ...
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Applications for this drug include the reduction of inflammation after eye surgery, [2] seasonal allergic conjunctivitis, uveitis, [5] and chronic forms of keratitis - such as adenoviral, Thygeson's keratitis, vernal keratoconjunctivitis,pingueculitis, giant papillary conjunctivitis, and episcleritis. [6]
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