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A schematic for long bone endochondral ossification. In developing bones, ossification commences within the primary ossification center located in the center of the diaphysis (bone shaft), [5] where the following changes occur: The perichondrium surrounding the cartilage model transforms into the periosteum. During this transformation, special ...
Diagram showing stages of endochondral ossification. Endochondral ossification is the formation of long bones and other bones. This requires a hyaline cartilage precursor. There are two centers of ossification for endochondral ossification. The primary center. In long bones, bone tissue first appears in the diaphysis (middle of shaft).
The process of endochondral ossification, which converts the cartilage models into bone, begins by the twelfth week of embryonic development. At birth, ossification of much of the bone has occurred, but the hyaline cartilage of the epiphyseal plate will remain throughout childhood and adolescence to allow for bone lengthening.
Infection: this is the most common complication of fractures and predominantly occurs in open fractures. Post-traumatic wound infection is the most common cause of chronic osteomyelitis in patients. Osteomyelitis can also occur following surgical fixation of a fracture. [8] Non-union: no progression of healing within six months of a fracture ...
Endochondral ossification occurs in long bones and most other bones in the body; it involves the development of bone from cartilage. This process includes the development of a cartilage model, its growth and development, development of the primary and secondary ossification centers , and the formation of articular cartilage and the epiphyseal ...
An ossification center is a point where ossification of the hyaline cartilage begins. The first step in ossification is that the chondrocytes at this point become hypertrophic and arrange themselves in rows. [1] The matrix in which they are imbedded increases in quantity, so that the cells become further separated from each other.
Endochondral ossification is the process of forming bone from cartilage and this is the usual method. This form of bone development is the more complex form: it follows the formation of a first skeleton of cartilage made by chondrocytes, which is then removed and replaced by bone, made by osteoblasts. Intramembranous ossification is the direct ...
Its lateral end is formed by intramembranous ossification while medially it is formed by endochondral ossification. It consists of a mass of cancellous bone surrounded by a compact bone shell. The cancellous bone forms via two ossification centres , one medial and one lateral, which fuse later on.