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Lupus erythematosus is a collection of autoimmune diseases in which the human immune system becomes hyperactive and attacks healthy tissues. [1] Symptoms of these diseases can affect many different body systems, including joints, skin, kidneys, blood cells, heart, and lungs.
Lupus, formally called systemic lupus erythematosus (SLE), is an autoimmune disease in which the body's immune system mistakenly attacks healthy tissue in many parts of the body. [1] Symptoms vary among people and may be mild to severe. [ 1 ]
Childhood-onset systemic lupus erythematosus (i.e., cSLE), also termed juvenile-onset systemic lupus erythematosus, juvenile systemic lupus erythematosus, and pediatric systemic lupus erythematosus, is a form of the chronic inflammatory and autoimmune disease, systemic lupus erythematosus (i.e., SLE), that develops in individuals up to 18 years old. [1]
Lupus vasculitis typically indicates a dismal prognosis, so early diagnosis is essential to a successful outcome. [2] The disease can affect small vessels or a single organ, and it can range in severity from a relatively mild condition to a multiorgan system disease with potentially fatal symptoms, like mesenteric vasculitis, [ 3 ] pulmonary ...
There are general symptoms like fever and weight loss, as well as specific symptoms depending on the specific organ system being affected and damaged. In fact, it’s so unpredictable that a diagnosis is given only when 4 or more out of eleven diagnostic criteria are met.
When there is proof of an autoimmune disease, but the disease does not correspond to any specific autoimmune disease (such as systemic lupus erythematosus (SLE), scleroderma, [2] mixed connective tissue disease, Sjögren syndrome, systemic sclerosis, polymyositis, dermatomyositis, or rheumatoid arthritis), it will be
Lupus nephritis is an inflammation of the kidneys caused by systemic lupus erythematosus (SLE) and childhood-onset systemic lupus erythematosus which is a more severe form of SLE that develops in children up to 18 years old; both are autoimmune diseases. [3] [4] It is a type of glomerulonephritis in which the glomeruli become inflamed.
In addition, onset of neuropsychiatric symptoms may happen prior to the diagnosis of lupus. [7] Due to the lack of uniform diagnostic standards, statistics about NPSLE vary widely. [8] Tests which aid in diagnosis include MRI, electrophysiological studies, psychiatric evaluation, and autoantibody tests. [9]
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