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Depolarization is essential to the function of many cells, communication between cells, and the overall physiology of an organism. Action potential in a neuron , showing depolarization, in which the cell's internal charge becomes less negative (more positive), and repolarization, where the internal charge returns to a more negative value.
A neuron receives signals from neighboring cells through branched, cellular extensions called dendrites.The neuron then propagates an electrical signal down a specialized axon extension from the basal pole to the synapse, where neurotransmitters are released to propagate the signal to another neuron or effector cell (e.g., muscle or gland).
Since basal and lateral membranes share the same determinants, another mechanism must make the difference between the two domains. Cell shape and contacts provide the likely mechanism. Lateral membranes are the site of contact between epithelial cells, whereas basal membranes connect epithelial cells to the basement membrane , an extracellular ...
This electrical polarization results from a complex interplay between protein structures embedded in the membrane called ion pumps and ion channels. In neurons, the types of ion channels in the membrane usually vary across different parts of the cell, giving the dendrites , axon , and cell body different electrical properties.
Most often, the threshold potential is a membrane potential value between –50 and –55 mV, [1] but can vary based upon several factors. A neuron's resting membrane potential (–70 mV) can be altered to either increase or decrease likelihood of reaching threshold via sodium and potassium ions.
A nerve impulse causes Na + to enter the cell, resulting in (b) depolarization. At the peak action potential, K + channels open and the cell becomes (c) hyperpolarized. Voltage gated ion channels respond to changes in the membrane potential. Voltage gated potassium, chloride and sodium channels are key components in the generation of the action ...
Polarization (physics), the ability of waves to oscillate in more than one direction; polarization of light allows the glare-reducing effect of polarized sunglasses Polarization (antenna) , the state of polarization (in the above sense) of electromagnetic waves transmitted by or received by a radio antenna
The smallest difference between the lower and upper currents used is the rheobase search precision: the "true" rheobase is somewhere between the two tested current values. Precision is also affected by thermal noise and stochastic nature of ion channels.