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These side effects are serious and some of them are permanent, and many remain a crucial concern for companies and healthcare professionals and substantial efforts are being encouraged to reduce the potential risks for future antipsychotics through more clinical trials and drug development.
Second-generation antipsychotics, including risperidone, are effective in the treatment of manic symptoms in acute manic or mixed exacerbations of bipolar disorder. [25] [26] [27] In children and adolescents, risperidone may be more effective than lithium or valproate, but has more metabolic side effects. [28]
The latter have a greater degree of anticholinergic and antihistaminergic activity, which can counteract dopamine-related side-effects. [172] Atypical antipsychotic drugs have a similar blocking effect on D 2 receptors; however, most also act on serotonin receptors, especially 5-HT 2A and 5-HT 2C receptors. Both clozapine and quetiapine appear ...
Lurasidone, sold under the brand name Latuda among others, is an antipsychotic medication used to treat schizophrenia and bipolar depression. [2] It is taken by mouth.. Common side effects include nausea, mild movement problems, sedation, and restlessness. [2]
Medications are used to reverse the symptoms of extrapyramidal side effects caused by antipsychotics or other drugs, by either directly or indirectly increasing dopaminergic neurotransmission. The treatment varies by the type of the EPS, but may involve anticholinergic agents such as procyclidine, benztropine, diphenhydramine, and trihexyphenidyl.
Like other antidepressants — and medications in general — it can cause a range of side effects that you should be aware of before using this medication. ... Antipsychotic and antianxiety ...
Serious side effects may include movement disorders including tardive dyskinesia and neuroleptic malignant syndrome. [6] Use in pregnancy and breastfeeding is generally not recommended. [10] It is a typical antipsychotic which is believed to work by reducing the action of dopamine in the brain. [6]
The traditional antipsychotic drugs are associated with tardive dyskinesia when used long-term; and parkinsonism, dystonia, dyskinesia, and akathisia when used short-term. Additional side effects can be school phobia (a form of separation anxiety), depression, weight gain, and cognitive blunting (dulling of cognitive ability).