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Benzyl bromide is an isomer, which has a bromine substituted for one of the hydrogens of toluene's methyl group, and it is sometimes named α-bromotoluene. Preparation [ edit ]
It produces theobromine, acetylthiophene, and p-bromotoluene as active pharmaceutical ingredients (APIs). Ipca sells these APIs and their intermediates globally. [6] It produces more than 150 formulations that include oral liquids, tablets, dry powders, and capsules. [7]
Benzyl bromide is used in organic synthesis for the introduction of the benzyl groups when the less expensive benzyl chloride is insufficiently reactive. [6] [7] Benzylations are often achieved in the presence of catalytic amounts of sodium iodide, which generates the more reactive benzyl iodide in situ. [3]
A laboratory route to o- and p-iodotoluene proceeds from toluene, which is treated with a mixture of iodine and nitric acid in an electrophilic aromatic substitution.The resulting mixture of o and p-iodotoluene is then separated by fractional freezing; cooling the mixture in an ice bath results in solidification of p-iodotoluene, which can then be isolated by filtration, while the o ...
4-Bromobenzaldehyde may be prepared in the laboratory in two steps by oxidation 4-bromotoluene. [4] In the first step, two bromine atoms are added to the methyl group of 4-bromotoluene by free radical bromination to form 4-bromobenzal bromide.
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Bromotoluene This page was last edited on 19 May 2023, at 21:33 (UTC). Text is available under the Creative Commons Attribution-ShareAlike 4.0 License ...
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