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Menopause, also known as the climacteric, is the time when menstrual periods permanently stop, marking the end of reproduction. [1] [6] [7] It typically occurs between the ages of 45 and 55, although the exact timing can vary. [8] Menopause is usually a natural change related to a decrease in circulating blood estrogen levels. [3]
During development, the outer parts of the two ducts fuse, forming a single urogenital canal that will become the vagina, cervix and uterus. [14] The cervix grows in size at a smaller rate than the body of the uterus, so the relative size of the cervix over time decreases, decreasing from being much larger than the body of the uterus in fetal ...
Menstrual cycle The menstrual cycle is a series of natural changes in hormone production and the structures of the uterus and ovaries of the female reproductive system that makes pregnancy possible. The ovarian cycle controls the production and release of eggs and the cyclic release of estrogen and progesterone. The uterine cycle governs the preparation and maintenance of the lining of the ...
Menopause affects women’s health and well-being on both micro and macro levels. Women who hit menopause before 45 are at increased risk of cardiovascular problems and dying earlier than women ...
The cervical canal is generally lined by "endocervical mucosa" which consists of a single layer of mucinous columnar epithelium. However, after menopause, the functional squamocolumnar junction moves into the cervical canal, and hence the distal part of the cervical canal may be lined by stratified squamous epithelium (conforming to a "type 3 transformation zone").
After menopause, the lining is often described as being atrophic. In contrast, endometrium that is chronically exposed to estrogens, but not to progesterone, may become hyperplastic . Long-term use of oral contraceptives with highly potent progestins can also induce endometrial atrophy .
It begins to involute with contractions of the smooth muscle of the uterus. It will contract midline with the umbilicus. It begins its contractions and by twelve hours after the birth it can be felt to be at the level of the umbilicus. [9] The uterus changes in size from one kilogram to 60-80 grams in the space of six weeks.
The absence of vaginal rugae seen in the normal vagina of a healthy woman may be an indication of a prolapsed bladder (cystocele) or rectocele. [13] [12] An enterocele, or bulging of the bowel into the vagina can also cause vaginal rugae to disappear. [16] The absence of vaginal rugae may also be an indicator of pelvic organ prolapse.
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