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Whereas the peritubular capillaries surround the cortical parts of the tubules, the vasa recta go into the medulla and are closer to the loop of Henle, [1] [2] and leave to ascend to the cortex. [3] [4] Terminations of the vasa recta form the straight venules, branches from the plexuses at the apices of the medullary pyramids.
Note 3: The efferent arterioles do not directly drain into the interlobular vein, but rather they go to the peritubular capillaries first. The efferent arterioles of the juxtamedullary nephron drain into the vasa recta.
The glomerular basement membrane of the kidney is the basal lamina layer of the glomerulus.The glomerular endothelial cells, the glomerular basement membrane, and the filtration slits between the podocytes perform the filtration function of the glomerulus, separating the blood in the capillaries from the filtrate that forms in Bowman's capsule. [1]
The blood exiting the efferent arterioles of these nephrons enter the vasa recta, which are straight capillary branches that deliver blood to the renal medulla. These vasa recta run adjacent to the descending and ascending loop of Henle and participate in the maintenance of the medullary countercurrent exchange system.
This results in a smaller capillary hydrostatic pressure, which causes an increased absorption of sodium ions into the vasa recta at the proximal tubule. Hence, a decrease in blood pressure results in less sodium chloride present at the distal tubule , where the macula densa is located.
The renal corpuscle is composed of two structures, the glomerulus and the Bowman's capsule. [3] The glomerulus is a small tuft of capillaries containing two cell types. . Endothelial cells, which have large fenestrae, are not covered by dia
When renal blood flow is reduced (indicating hypotension) or there is a decrease in sodium or chloride ion concentration, the macula densa of the distal tubule releases prostaglandins (mainly PGI2 and PGE2) and nitric oxide, which cause the juxtaglomerular cells lining the afferent arterioles to release renin, activating the renin–angiotensin–aldosterone system, to increase blood pressure ...
The descending vasa recta, ascending vasa recta vessels, and the loop of Henle together form the countercurrent system of the kidney. In the afferent arteriole, blood is supplied at high pressure, which promotes filtration, and in the efferent arteriole, it is at low pressure, which promotes reabsorption .