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Procalcitonin (PCT) is a peptide precursor of the hormone calcitonin, the latter being involved with calcium homeostasis. It arises once preprocalcitonin is cleaved by endopeptidase . [ 1 ] It was first identified by Leonard J. Deftos and Bernard A. Roos in the 1970s. [ 2 ]
A 2013 review concluded moderate-quality evidence exists to support the use of the procalcitonin level as a method to distinguish sepsis from non-infectious causes of SIRS. [45] The same review found the sensitivity of the test to be 77% and the specificity to be 79%.
The use of eosinopenia as a diagnostic tool in sepsis is debatable. [10] Although there is a high incidence of eosinopenia in sepsis, it is not more effective as a biomarker than more commonly utilized indicators of sepsis, such as procalcitonin (PCT) and C-reactive protein (CRP). [10]
-->Cancer More so, it is especially effective in diagnosing major life threatening episodes in cancer patients, such as bacteremia and sepsis. Procalcitonin is a reliable way to monitor recurrence of medullary thyroid carcinoma. In detecting cancer recurrence, PCT had a sensitivity and specificity of 96% and 96%, respectively.[73]
A major rockslide prompted two highways to be shut down in Colorado over the weekend and witnesses captured the frightening moment on video. Highways 96 and 165 from Wetmore to Westcliffe in ...
Growth hormone treatment is a safe and effective therapy that’s often used to treat children and adults with a deficiency in human growth hormone (also known as HGH or somatropin).. Naturally ...
Regardless of what your thoughts are on Subway, you have to admit that the fast food chain proudly holds its footlong crown high.After solidifying its place in fast food lore with those beloved $5 ...
Procalcitonin-guided antibiotic therapy also reduced the antibiotic use duration by 2.4 days, and there were fewer antibiotic side effects. This means that procalcitonin is useful for guiding whether to use antibiotics for acute respiratory infections and the duration of the antibiotic. [23]