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Vitamin B 12 is derived from a tetrapyrrolic structural framework created by the enzymes deaminase and cosynthetase which transform aminolevulinic acid via porphobilinogen and hydroxymethylbilane to uroporphyrinogen III. The latter is the first macrocyclic intermediate common to heme, chlorophyll, siroheme and B 12 itself.
Vitamin B 12 deficiency is preventable with supplements, which are recommended for pregnant vegetarians and vegans, and not harmful in others. [2] Risk of toxicity due to vitamin B 12 is low. [2] Vitamin B 12 deficiency in the US and the UK is estimated to occur in about 6 percent of those under the age of 60, and 20 percent of those over the ...
Methylcobalamin is equivalent physiologically to vitamin B 12, [3] and can be used to prevent or treat pathology arising from a lack of vitamin B 12 intake (vitamin B 12 deficiency). Methylcobalamin is also used in the treatment of peripheral neuropathy, diabetic neuropathy, and as a preliminary treatment for amyotrophic lateral sclerosis. [4]
B12 is found in a wide array of animal-based foods, as it's produced by a gut bacteria that is then accumulated in the muscle tissue of most herbivorous animals, including fish, cows, chickens ...
MyKind Organics Vegan B12 Spray. Made with methylcobalamin and oodles of organic fruit and botanicals, one spray a day tastes like raspberries while delivering 500 micrograms of vitamin B12. Plus ...
It has been thought that if someone is deficient in vitamin B 12 and folic acid, the vitamin B 12 deficiency must be treated first. However, the basis for this has been challenged, although due to ethical considerations it is no longer able to be tested if "neuropathy is made more severe as a result of giving folic acid to vitamin B 12 ...
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