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In a ground-breaking experiment, researchers have successfully created the first human-monkey chimera. Scientists Report Creating the First Embryo With Human and Non-Human Primate Cells Skip to ...
A human chimera is a human with a subset of cells with a distinct genotype than other cells, that is, having genetic chimerism.In contrast, an individual where each cell contains genetic material from a human and an animal is called a human–animal hybrid, while an organism that contains a mixture of human and non-human cells would be a human-animal chimera.
Scientists based in China have created a monkey chimera with two sets of DNA, experimental work they say could ultimately benefit medical research and the conservation of endangered species.
The embryos were made by injecting human stem cells into macaque embryos as part of research into early human development. Scientists created a hybrid human-monkey embryo in a lab, sparking ...
As with those embryos, the human-monkey chimeras were reportedly only allowed to develop for a few weeks. Although development was stopped prior to the formation of a nervous system or organs, avoiding more severe ethical concerns, the research was reportedly carried out in China to avoid legal issues.
The development of methodologies for culturing embryos, including non-human primates, and creating synthetic mammalian embryos. [23] [24] Development of technologies that allow differentiation of human cells inside embryos of different species. These results may allow for the generation of human tissues and organs. [25] [26] [27] [28]
Of the six, one baby monkey was born alive and managed to survive for 10 days. Analysis showed this male newborn had donor stem cells in 26 different types of tissue, ranging from 21% to up to 92%.
A human chimera, on the other hand, consists only of human cells, from different zygotes.) Examples of human–animal hybrids mainly include humanized mice that have been genetically modified by xenotransplantation of human genes. [2] Humanized mice are commonly used as small animal models in biological and medical research for human ...
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