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Epidermodysplasia verruciformis (EV) is a skin condition characterised by warty skin lesions. [1] It results from an abnormal susceptibility to HPV infection (HPV) and is associated with a high lifetime risk of squamous cell carcinomas in skin. [1]
A range of types of wart have been identified, varying in shape and site affected, as well as the type of human papillomavirus involved. [6] [7] These include: Common wart (verruca vulgaris), [8] a raised wart with a roughened surface, most common on hands, but can grow anywhere on the body. Sometimes known as a Palmer wart or Junior wart.
Because only the top layers of the epidermis are involved, seborrheic keratoses are often described as having a "pasted on" appearance. Some dermatologists refer to seborrheic keratoses as "seborrheic warts", because they resemble warts, but strictly speaking, the term "warts" refers to lesions that are caused by the human papillomavirus. [9]
Common warts have a characteristic cauliflower-like surface and are typically slightly raised above the surrounding skin. Cutaneous HPV types can cause genital warts but are not associated with the development of cancer. [citation needed] Plantar warts are found on the soles of the feet; they grow inward, generally causing pain when walking.
A plantar wart is a wart occurring on the bottom of the foot or toes. [5] Its color is typically similar to that of the skin. [2] Small black dots often occur on the surface. [5] One or more may occur in an area. [2] They may result in pain with pressure such that walking is difficult. [2] They are caused by the human papillomavirus (HPV). [2]
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Giant condyloma acuminatum (also known as a Buschke–Löwenstein tumor [1]) is a rare cutaneous condition characterized by an aggressive, wart-like growth that is a verrucous carcinoma. [2]: 409 It is attributed to human papillomavirus. [3] Due to their size, these tumors can be locally invasive and destructive.
Because the TVC's entry point usually is the site of a trauma, wound or puncture in the skin (during an autopsy, for example), the most frequent site for the wart are the hands. But it can occur anywhere in the skin, such as in the sole of the feet, in the anus , and, in the case of children from developing countries , in the buttocks and knees .