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Although this method can distinguish essential tremor from Parkinson's syndrome, it is unable to distinguish between Parkinson's disease, Dementia with Lewy bodies, Parkinson's disease dementia, [3] multiple system atrophy or progressive supranuclear palsy. There is evidence that DaTSCAN is accurate in diagnosing early Parkinson's. [4] [5]
FAB is useful in the differential diagnosis of neurological diseases [3] including Parkinson's disease, corticobasal degeneration, frontotemporal dementias, Alzheimer's disease, Huntington's disease, progressive supranuclear palsy, [2] and dementia with Lewy bodies. [4]
Dementia with Lewy bodies and Parkinson's disease dementia are similar in many ways, suggesting there may be a common pathophysiological mechanism, with PDD and DLB at opposite ends of a Lewy body disease spectrum, [2] and a shared component of protein deposits in Lewy bodies and Lewy neurites. [17]
"A new blood-based diagnostic test would be a major advancement for Parkinson’s disease, which afflicts 10 million people worldwide and is the second most common neurodegenerative disease after ...
Like Lewy bodies, Lewy neurites are a feature of α-synucleinopathies such as dementia with Lewy bodies, Parkinson's disease, and multiple system atrophy. [21] They are also found in the CA2-3 region of the hippocampus in Alzheimer's disease. [21]
Researchers say a new blood test may be able to detect the potential progression of Parkinson's disease up to 7 years before symptoms appear ... test but can diagnose the disease ... Lewy bodies ...
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