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Simple columnar epithelium is a single layer of columnar epithelial cells which are tall and slender with oval-shaped nuclei located in the basal region, attached to the basement membrane. In humans, simple columnar epithelium lines most organs of the digestive tract including the stomach , and intestines .
By layer, epithelium is classed as either simple epithelium, only one cell thick (unilayered), or stratified epithelium having two or more cells in thickness, or multi-layered – as stratified squamous epithelium, stratified cuboidal epithelium, and stratified columnar epithelium, [8]: 94, 97 and both types of layering can be made up of any of ...
The cells in the respiratory epithelium are of five main types: a) ciliated cells, b) goblet cells, c) brush cells, d) airway basal cells, and e) small granule cells (NDES) [6] Goblet cells become increasingly fewer further down the respiratory tree until they are absent in the terminal bronchioles; club cells take over their role to some extent here. [7]
Barrett's esophagus is a condition in which there is an abnormal (metaplastic) change in the mucosal cells lining the lower portion of the esophagus, from stratified squamous epithelium to simple columnar epithelium with interspersed goblet cells that are normally present only in the small intestine and large intestine.
In the oesophagus, pharynx and external anal canal the epithelium is stratified, squamous and non-keratinising, for protective purposes. In the stomach, the epithelium is simple columnar, and is organised into gastric pits and glands to deal with secretion. [1] In the small intestine, epithelium is simple columnar and specialised for absorption.
Simple columnar, non-ciliated: intestinal epithelium: digestive: rectum: Simple columnar, non-ciliated - digestive: anus: Stratified squamous, non-keratinized superior to Hilton's white line Stratified squamous, keratinized inferior to Hilton's white line - digestive: gallbladder: Simple columnar, non-ciliated - endocrine: thyroid follicles ...
The duct is lined by a layer of simple columnar epithelium resting on a thin basement membrane. The epithelium is composed primarily of principal cells and α-intercalated cells. [7] The simple columnar epithelium of the collecting duct system transitions into urothelium near the junction of a papillary duct and a minor calyx. [6]
A brush border (striated border or brush border membrane) is the microvillus-covered surface of simple cuboidal and simple columnar epithelium found in different parts of the body. Microvilli are approximately 100 nanometers in diameter and their length varies from approximately 100 to 2,000 nanometers.