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  2. Nortriptyline - Wikipedia

    en.wikipedia.org/wiki/Nortriptyline

    Nortriptyline is an active metabolite of amitriptyline by demethylation in the liver. Chemically, it is a secondary amine dibenzocycloheptene and pharmacologically it is classed as a first-generation antidepressant. [36] Nortriptyline may also have a sleep-improving effect due to antagonism of the H 1 and 5-HT 2A receptors. [37]

  3. SSRIs: Everything You Need to Know Before Starting Them - AOL

    www.aol.com/ssris-everything-know-starting-them...

    The nortriptyline group experienced moderate weight gain. However, antidepressants don’t affect everyone equally, so there could still be a link between Lexapro and weight changes or other SSRIs ...

  4. Your Guide to the 6 Most Common Types of Depression ... - AOL

    www.aol.com/6-types-depression-medications...

    Medications for Depression: An Overview. Antidepressants are a class of medications used very commonly to treat depression. In fact, nearly 13 percent of people 12 and over in the U.S. used ...

  5. Selective serotonin reuptake inhibitor - Wikipedia

    en.wikipedia.org/wiki/Selective_serotonin...

    GAD is a common disorder of which the central feature is excessive worry about a number of different events. Key symptoms include excessive anxiety about multiple events and issues, and difficulty controlling worrisome thoughts, that persists for at least 6 months.

  6. Serotonin–norepinephrine reuptake inhibitor - Wikipedia

    en.wikipedia.org/wiki/Serotonin–norepinephrine...

    During this time development of distinctively different antidepressant agents was also researched. Imipramine became the first clinically useful tricyclic antidepressant (TCA). Imipramine was found to affect numerous neurotransmitter systems and to block the reuptake of norepinephrine and serotonin from the synapse , therefore increasing the ...

  7. Monoamine reuptake inhibitor - Wikipedia

    en.wikipedia.org/wiki/Monoamine_reuptake_inhibitor

    A monoamine reuptake inhibitor (MRI) [1] is a drug that acts as a reuptake inhibitor of one or more of the three major monoamine neurotransmitters serotonin, norepinephrine, and dopamine by blocking the action of one or more of the respective monoamine transporters (MATs), which include the serotonin transporter (SERT), norepinephrine transporter (NET), and dopamine transporter (DAT).

  8. Second-generation antidepressant - Wikipedia

    en.wikipedia.org/wiki/Second-generation...

    The second-generation antidepressants are a class of antidepressants characterized primarily by the era of their introduction, approximately coinciding with the 1970s and 1980s, rather than by their chemical structure or by their pharmacological effect.

  9. Serotonin–norepinephrine–dopamine reuptake inhibitor

    en.wikipedia.org/wiki/Serotonin–norepinephrine...

    This drug does not cause sexual dysfunction or weight gain like the SSRIs but has a higher incidence of nausea. Methylphenidate is a much more reliable example of an NDRI (the action that it displays on the DAT usually getting preferential treatment).

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